full free access: PLoS ONE: Genetic Analysis of the Early Natural History of Epithelial Ovarian Carcinoma

Conclusions/Significance

Together, these data indicate that EOC frequently arises in ovarian cystic inclusions, is preceded by an identifiable dysplastic precursor lesion, and that increased cell proliferation, decreased apoptosis, and aneuploidy are likely to represent very early aberrations in ovarian tumorigenesis.

media item: Study Makes Strides in Understanding Ovarian Cancer (cysts/BRCA/sporadic)

Important: see post April 26th -  full free access:
 PLOS One: Genetic Analysis of the Early Natural History of Epithelial Ovarian Carcinoma
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Media article: 
"This is the first study giving very strong evidence that a substantial number of ovarian cancers arise in inclusion cysts and that there is indeed a precursor lesion that you can see, put your hands on, and give a name to," lead author Jeff Boyd, chief scientific officer at Fox Chase Cancer Center in Philadelphia, said in a news release. "Ovarian cancer most of the time seems to arise in simple inclusion cysts of the ovary, as opposed to the surface epithelium."...cont'd

please read - for followers (blog)

April 26th, 2010: Apologies - tech issues - blog posts will be sporadic for the next day or so, please continue to check back for those not on auto-subscribe/feeds

Ontario Institute for Cancer Research Announces Three New Equity Investments -- TORONTO, April 26 /PRNewswire/ --

Note: press release has further information on the investments:

1)Novel Cellular Immunotherapy for Cancer;
2)Next Generation Biomarker Analysis Technology;
3)Rapid, Sensitive Technology for Biomarker Analysis

News: AACR: Nodectomy Helps in Carcinosarcoma - in Meeting Coverage, AACR

"Lymphadenectomy was associated with significant improvement in survival (P<0.001) in patients with ovarian and uterine carcinosarcomas, but the procedure was not performed as often in those with ovarian disease.
"Improved survival observed in the lymphadenectomy group argues in favor of routinely performing lymph node dissection in patients with uterine and ovarian carcinosarcoma," Gunjal Garg, MD, of Detroit Medical Center, and colleagues concluded in a poster presentation at the American Association for Cancer Research.
Carcinosarcomas are malignant mixed mullerian tumors. Carcinosarcomas that arise in the female genital tract are rare but associated with poor prognosis. Previous studies demonstrated that tumors of similar histology and originating in nearby organs might be biologically distinct entities because of involvement with different molecular pathways, Garg and colleagues noted..."cont'd

Leading Women's Organizations Applaud Release of New Report On Women and Lung Cancer -- WASHINGTON, April 26 /PRNewswire-USNewswire/ --

News: AACR: Combo Therapy Stymies Ovarian Cancer - in Meeting Coverage, "IMC-3G3"

Computers in Human Behavior : Empowering processes in online support groups among people living with HIV/AIDS: A comparative analysis of ‘lurkers’ and ‘posters’

Note: 'lurker'/online study

Inhibiting the inhibitors: evaluating agents targeting cancer immunosuppression; Expert Opinion on Biological Therapy (abstract)

new journal (and index of abstracts) The Human Genome Organisation (HUGO)

The Human Genome Organisation (HUGO)

job positing 'The Underwear Affair' - Community Outreach/Salesperson Jobs in Toronto, Ontario - CauseForce, Inc.

job posting (breast cancer) - Master of Ceremonies for Fundraising Events Jobs in Toronto, Ontario - CauseForce, Inc.

patient safety news (U.S.): Infection checklist effort expands, but national rates unchanged