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Thursday, August 12, 2010

Medical News: Cancer Biomarkers Missing in Action - Ovarian Cancer - Medscape



With a handful of possible exceptions, Diamandis wrote, "very few, if any, molecules have been identified that are expressed only by a cancer tissue but not by the corresponding normal tissue."
Cancer biomarkers are missing in action despite the availability of "highly sophisticated and powerful technologies" to discover them, as well as large investments, Diamandis wrote, adding that the last biomarker approved by the FDA -- in 2009 -- was HE4 protein, indicated for monitoring recurrence but not early detection of ovarian cancer."

Action Points  
  • Note that this commentary documents the hazards of reports on promising biomarkers for cancer screening.


  • The author points out that one of the major problems is finding biomarkers released in significant amounts from asymptomatic (usually small) tumors, but not from normal tissues.

Expert Analysis: Clinical Care Options Oncology - Ovarian Cancer



INDEPENDENT CONFERENCE COVERAGE
2010 American Society of Clinical Oncology Annual Meeting*

*CCO is an independent medical education company that provides state-of-the-art medical information to healthcare professionals through conference coverage and other educational programs.


To:

CCO member


From:

Thomas J. Herzog, MD
Columbia University College of Physicians and Surgeons
New York, New York


Subject:

CME/CE-Certified Expert Analysis From Chicago


Click to Access:

Ovarian Cancer



While attending the clinical oncology meeting in Chicago, Illinois, I met with Bradley J. Monk, MD, to review the clinical implications of recent studies in ovarian cancer. Our discussion is available on the Clinical Care Options Web site as a CME/CE-certified Expert Analysis.

Select topics include:

  • Bevacizumab-Based First-line Regimen and Maintenance Therapy for Advanced Ovarian Cancer
  • First-line Gemcitabine/Carboplatin vs Paclitaxel/Carboplatin, Followed by Paclitaxel Maintenance for Advanced Epithelial Ovarian Cancer
  • Frontline PLD/Carboplatin vs Paclitaxel/Carboplatin for Advanced Ovarian Cancer
  • Exploration of PARP Inhibitors in Ovarian Cancer With and Without BRCA Mutations
  • New Antiangiogenesis Inhibitor for the Treatment of Recurrent Ovarian Cancer: AMG 386
  • Novel Monoclonal Antibody for the Treatment of Platinum-Sensitive Epithelial Ovarian Cancer: Farletuzumab
  • Novel Vincristine-Based Agent for the Treatment of Platinum-Resistant Advanced Ovarian Cancer: EC125
  • Nab-Paclitaxel Plus Bevacizumab in Platinum-Resistant Primary Epithelial Ovarian Cancer or Primary Peritoneal Cancer
  • Novel Irinotecan-Based Agent for the Treatment of Platinum-Resistant/Refractory Ovarian Cancer: NKTR-102
  • Platinum-Free Interval Extension With Trabectedin/PLD in Partially Platinum-Sensitive Recurrent Ovarian Cancer
  • 2-Step Screening Strategy for Ovarian Cancer Using Annual CA-125 Measurement and Possible Transvaginal Ultrasound

To review this CME/CE-certified Expert Analysis, click here.

This Expert Analysis is located online at:
http://clinicaloptions.com/Oncology/Conference%20Coverage/Clin%20Onc%20June%202010.aspx

Institutional financial conflicts of interest policies at Canadian academic health science centres: a national survey - full free access




Facebook loophole reveals names, pictures with sign-on errors | Security - CNET News



Facebook loophole reveals names, pictures with sign-on errors | Security - CNET News

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Disadvantaged face the hardest fight against cancer



Note: to cancer patients and their families this is not a surprise, I would suspect via media reports, past and present, that the public is wiser as well (aka: "the Wisdom of Crowds")

"To many Canadians this finding might come as a surprise."

Read more: http://www.vancouversun.com/health/Disadvantaged+face+hardest+fight+against+cancer/3384687/story.html#ixzz0wMeKYWYt