Tuesday, September 28, 2010
Mayo Collaboration Finds Source of Breast Drug Side Effect - Drugs.com MedNews (aromatase inhibitors/arthritis/bone pain)
Mayo Collaboration Finds Source of Breast Drug Side Effect
Pharmacogenomic discovery allows for improved cancer therapy
ROCHESTER, Minn. — Mayo Clinic researchers and their international colleagues have discovered genetic variants that lead to severe arthritis for a subset of women when taking aromatase inhibitors to treat their breast cancer. This serious side effect is so painful that many women halt their lifesaving medication. The findings appear today in the online issue of Journal of Clinical Oncology.
Read more: http://www.drugs.com/clinical_trials/mayo-collaboration-finds-source-breast-10214.html#ixzz10seG0Pnb
Quality of pathology reports for advanced ovarian cancer: Are we missing essential information? An audit of 479 pathology reports from the EORTC-GCG 5
Quality of pathology reports for advanced ovarian cancer: Are we missing essential information? An audit of 479 pathology reports from the EORTC-GCG 55971/NCIC-CTG OV13 neoadjuvant trial
CONCLUSION: This audit of ovarian cancer pathology reports reveals that in a substantial number of reports basic pathologic data are missing, with possible adverse consequences for the quality of cancer care. Specialisation by pathologists and the use of standardised synoptic reports can lead to improved quality of reporting. Further research is needed to better define pre- and post-operative diagnostic criteria for ovarian cancer treated with neoadjuvant chemotherapy.
Declaration: The World Cancer Declaration - A call to action from the global cancer community | Union for International Cancer Control
Targets: by 2020
- Sustainable delivery systems will be in place to ensure that effective cancer control programmes are available in all countries
- The measurement of the global cancer burden and the impact of cancer control interventions will have improved significantly
- Global tobacco consumption, obesity and alcohol intake levels will have fallen significantly
- Populations in the areas affected by HPV and HBV will be covered by universal vaccination programmes
- Public attitudes towards cancer will improve and damaging myths and misconceptions about the disease will be dispelled
- Many more cancers will be diagnosed when still localized through the provision of screening and early detection programmes and high levels of public and professional awareness about important cancer warning signs
- Access to accurate cancer diagnosis, appropriate cancer treatments, supportive care, rehabilitation services and palliative care will have improved for all patients worldwide
- Effective pain control measures will be available universally to all cancer patients in pain
- The number of training opportunities available for health professionals in different aspects of cancer control will have improved significantly
- Emigration of health workers with specialist training in cancer control will have reduced dramatically
- There will be major improvements in cancer survival rates in all countries
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