Latest advances in medical oncology: highlights from Milan ESMO 2010 annual congress Therapeutic Advances in Medical Oncology January 2011 3: 3-9, doi:10.1177/1758834010390407
Tuesday, December 21, 2010
abstract/full access: Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995–2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data : The Lancet
Note: Full access to article is free after registration (free)
Cancer survival is a key measure of the effectiveness of health-care systems. Persistent regional and international differences in survival represent many avoidable deaths. Differences in survival have prompted or guided cancer control strategies. This is the first study in a programme to investigate international survival disparities, with the aim of informing health policy to raise standards and reduce inequalities in survival.
Methods Data from population-based cancer registries in 12 jurisdictions in six countries were provided for 2·4 million adults diagnosed with primary colorectal, lung, breast (women), or ovarian cancer during 1995—2007, with follow-up to Dec 31, 2007.
CBC News - Health - Cancer survival study 'good news' for Canada (small reference to ovarian cancer) including public comments
Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study : The Lancet Oncology
EPCAM deletion carriers have a high risk of colorectal cancer; only those with deletions extending close to the MSH2 promoter have an increased risk of endometrial cancer. These results underscore the effect of mosaic MSH2 deficiency, leading to variable cancer risks, and could form the basis of an optimised protocol for the recognition and targeted prevention of cancer in EPCAM deletion carriers.
Family History of Cancer and Cancer Risks in Women with BRCA1 or BRCA2 Mutations — J. Natl. Cancer Inst.
Note: some stats taken out for ease of reading
"...Among women with a BRCA1 mutation, the risk of breast cancer increased by 1.2-fold for each first-degree relative with breast cancer before age 50 years and the risk of ovarian cancer increased by 1.6 fold for each first- or second-degree relative with ovarian cancer ...cont'd
Note: ovarian cancer - 8th in incidence rate; 5th in death rate
Donna J. Stecker Guest Book: sign their guest book, share your condolences, or read their obituary at The Washington Post
"...The partnership between the EU and the US, the two world leaders in eHealth, sends a strong signal to all stakeholders that common standards and interoperability bring opportunities for a global approach for the benefit of patients, health systems and the market"