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Thursday, December 30, 2010

abstract: Ventral hernia following primary laparotomy for ovarian, fallopian tube, and primary peritoneal cancers



An incisional hernia occurs in an area of weakness caused by an incompletely-healed surgical wound. Since median incisions in the abdomen are frequent for abdominal exploratory surgery, ventral incisional hernias are termed ventral hernias. ...
en.wikipedia.org/wiki/Ventral_hernia

OBJECTIVES: To evaluate the incidence and risk factors for ventral hernia development following primary laparotomy for ovarian, fallopian tube, and peritoneal cancers.
CONCLUSIONS: The development of ventral hernia is a significant postoperative morbidity in patients undergoing primary surgery for ovarian, tubal, or peritoneal cancer. Independent associations with hernia development include: BMI and IP chemotherapy by Year 1, and BMI, wound complications and advanced stage by Year 2.

abstract: CA 125 normalization with chemotherapy is independently predictive of survival in advanced endometrial cancer



Abstract

OBJECTIVE: Changes in CA 125 with chemotherapy predict outcome for epithelial ovarian cancer. There is no such data for advanced endometrial cancer.
CONCLUSION: As with epithelial ovarian cancer, changes in CA 125 are highly predictive of outcome for advanced, chemotherapy treated endometrial cancer.

abstract: Satisfaction with ovarian carcinoma risk-reduction strategies among women at high risk for breast and ovarian carcinoma




full free access: Reexamining the Physical Examination for Obese Patients - — JAMA



Table. Practical Suggestions for Performing the Physical Examination

full free access: Guidelines Loading... American Society of Hematology Guidelines Epoetin and Darbepoetin



Guidelines

American Society of Hematology Guidelines

Epoetin and Darbepoetin
"American Society of Hematology/American Society of Clinical Oncology 2010 clinical practice guideline update on the use of epoetin and darbepoetin"The latest research and evidence-based clinical guidelines about the use of epoetin for the treatment of cancer-related anemia.
  • Data Supplement 

    "Future directions
    There is clear evidence regarding the ability of ESAs to increase
    Hb and avoid transfusions. There is also evidence of harm
    associated with their use. Perhaps the most pressing need for
    additional research is studies that further clarify the mechanisms of
    harm and, particularly, the groups of patients or circumstances of
    clinical use that are least associated with these risks. This understanding
    is paramount to the ability of clinicians to extend the
    benefit of these drugs while reducing the risks."

full free access: American Society of Clinical Oncology/American Society of Hematology Clinical Practice Guideline Update on the Use of Epoetin and Darbepoetin in Adult Patients With Cancer — JCO



"Editor's Note: This document represents an abridged version of the complete guideline update and contains updated recommendations with a brief discussion of the relevant literature. Readers should refer to the complete guideline update, which includes a comprehensive discussion and analysis of the literature and more evidence tables. The complete guideline is available at www.asco.org/guidelines/esa and http://www.hematology.org/guidelines/esa/."