Increased Risk of CancerIf a parent carries a Lynch mutation there is a 50-50 chance that their child will inherit Lynch syndrome with
- 60 to 80 percent increased lifetime risk of colorectal cancer.
- 40 to 70 percent increased risk of endometrial cancer (cancer of the uterus lining).
- 13 percent increased risk for stomach cancer
- 12 percent increased risk of ovarian cancer.
- smaller, but significant risk of small intestine, urinary tract, heptobiliary (liver, gall bladder and bile ducts), skin, and brain cancers.
- Some families may also have increased risk for breast cancer.
Lynch Syndrome is also noted for multiple primary cancers (different cancers in one person)