Monday, July 11, 2011
irrespective of location, C. difficile is an ongoing and unresolved issue (both hospital/non-hospital acquired) and in particular for cancer patients;
it seems the SARS cases of the past have not impacted the 'lessons-not-learned' category and yet people continue to die due to lapses in policy amongst other issues/concerns, patient safety efforts (eg. handwashing...) still need to be addressed (obviously)
abstract - Cancer Letters : Ovarian Clear Cell Carcinoma as a Stress-Responsive Cancer: Influence of the Microenvironment on the Carcinogenesis and Cancer Phenotype
► Ovarian endometriosis is known to transform into ovarian cancer, but its etiology is not clarified.
► A stressful microenvironment within the endometriotic cyst may lead to cancer development.
► Ovarian clear cell carcinoma has unique gene expressions, which may serve as a molecular marker.
► Carcinogenic microenvironment affects the phenotype, character and gene expression of a cancer.
► We might be able to develop new treatment based on the analysis of the influence of microenvironment.
"Targeting src kinase with combination of dasatinib and oxaliplatin may be an attractive approach in this disease."
Abstract/full free access: Sustained platelet-sparing effect of weekly low dose paclitaxel allows effective, tolerable delivery of extended dose dense weekly carboplatin in platinum resistant/ refractory epithelial ovarian cancer
abstract - The Lancet Oncology : Evolution of platinum resistance in high-grade serous ovarian cancer
ICGC Releases New Genomic Data on Cancer Ahead of Schedule -- TORONTO, July 11, 2011 /PRNewswire/ --
"...The data include new submissions to the ICGC from The Cancer Genome Atlas (TCGA) in the United States, which has contributed information on about 10 types of cancer affecting the blood, brain, colon, kidney, lung, ovaries, rectum, and uterus, including data from a study of 500 ovarian cancer patients published in the journal Nature on June 30......