Wednesday, July 13, 2011
abstract: Laparoscopic-assisted cytoreduction for primary advanced ovarian cancer: Success, morbidity and survival
OBJECTIVES: Several studies addressed the association between antibiotic use and breast cancer risk. The objective of this study was to assess the association between antibiotic use and risk of cervical, ovarian, and uterine cancer.
Video Guide: How to Use the NCI Clinical Trials Search Form
The NCI Clinical Trials Search Form allows you to search a list of more than 8,000 clinical trials now accepting participants. The list includes trials supported by NCI, pharmaceutical companies, academic institutions, and other research organizations. The following two videos show users how to use the form and review the results. For additional guidance, see
Help Using the NCI Clinical Trials Search Form.
(Opinion) Letter of Response: Cancer Test Failure - NYTimes.com (“How Bright Promise in Cancer Testing Fell Apart” )
Cancer Test Failure
Published: July 12, 2011
To the Editor:
Re “How Bright Promise in Cancer Testing Fell Apart” (front page, July 8):
" The strongest evidence for reproductive disease due to asbestos is in regard to ovarian cancer. Unfortunately, effects on fertility and the developing fetus are under-studied. The possibility of other asbestos-induced health effects does exist. These include brain-related tumors, blood disorders due to the mutagenic and hemolytic properties of asbestos, and peritoneal fibrosis. It is clear from the literature that the adverse properties of asbestos are not confined to the pulmonary system."
Cochrane review: Short versus long duration infusions of paclitaxel for any advanced adenocarcinoma.
OBJECTIVES:To assess the effectiveness and toxicity of short versus long infusions of paclitaxel for any advanced adenocarcinoma.
"Adverse events were not comprehensively reported for any of the other comparisons. Outcomes were incompletely documented and QoL outcomes were not reported in any of the trials. The strength of the evidence is weak in this review as it is based on meta analyses of very few trials or single trial analyses and all trials were at moderate risk of bias and two were published in abstract form only."
abstract: A comparison of international breast cancer guidelines - Do the national guidelines differ in treatment recommendations? USA, Canada, Australia, the UK, and Germany
(USA, Canada, Australia, the UK, and Germany)
CONCLUDING STATEMENT: Considering that the development of guidelines is a very expensive and resource-intensive task the question arises whether the development of national guidelines in numerous countries is worth the effort since the recommendations differ only marginally.