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Friday, November 09, 2012

Clinicopathologic features of brain metastases from gynecologic malignancies: A retrospective study of 139 cases (KCOG-G1001s trial)



 Clinicopathologic features of brain metastases from gynecologic malignancies: A retrospective study of 139 cases (KCOG-G1001s trial)

Highlights

► Brain metastases from ovarian/tubal/peritoneal cancer revealed better prognosis compared to those from corpus cancer or cervical cancer.
► Ovarian/tubal/peritoneal origin, KPS > 70, single metastasis, absence of extracranial disease, cranial surgery, radiotherapy, and chemotherapy are independent favorable prognostic factors.
► Aggressive multimodal therapy is warranted in the treatment of brain metastases from gynecologic malignancies in carefully selected patients.

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