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Paraneoplastic cerebellar degeneration associated with ovarian cancer
Published online on: Wednesday, November 7, 2012 |
Doi: 10.3892/ol.2012.1016 |
Abstract:
Paraneoplastic
cerebellar degeneration (PCD) is a rare neurological disorder
characterized by a widespread loss of Purkinje cells associated with a
progressive pancerebellar dysfunction. PCD often precedes the cancer
diagnosis by months to years. Here, we report the case of a 64‑year‑old
woman who developed PCD symptoms, associated with high levels of anti‑Yo
antibodies, one year after a previous diagnosis of ovarian cancer.
Clinical features, pathogenesis and treatment of PCD associated with
cancer are discussed according to previous studies.
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