Bill C-38 protest has 13,000 websites going dark across Canada this June | Canada Politics - media (c-38 bill/Canadian healthcare)

Bill C-38 protest has 13,000 websites going dark across Canada this June | Canada Politics

"When it comes to politics, Canadians are generally an apathetic bunch. Often, a controversy will brew and within a week or two we forget about it and move on.

It appears Bill C-38 is one issue we're not willing to let go....

Bill C-38

Jobs, Growth and Long-term Prosperity Act

An Act to implement certain provisions of the budget tabled in Parliament on March 29, 2012 and other measures

 

C-38: What it means for health care (media)

IL-13 regulates cancer invasion and metastasis through IL-13Rα2 via ERK/AP-1 pathway in mouse model of human ovarian cancer.

IL-13 regulates cancer invasion and metastasis through IL-13Rα2 via ERK/AP-1 pathway in mouse model of human ovarian cancer

"Taken together, IL-13Rα2 is involved in cancer metastasis through activation of ERK/AP-1 and that targeting IL-13Rα2 might not only directly kill primary tumors but also prevent cancer metastasis."

Health News - Enhanced data access to benefit cancer researchers and patients

Health News - Enhanced data access to benefit cancer researchers and patients

Neurocognitive function impairment after whole brain radiotherapy for brain metastases: actual assessment

 Neurocognitive function impairment after wholebrain radiotherapy for brain metastases: actual assessment


 Conclusion
......The results of this review will enable physicians to inform
patients about benefits and risks of these two treatment options.

paywalled: Bevacizumab-induced perforation of the gastrointestinal tract: clinical and radiographic findings in 11 patients

Bevacizumab-induced perforation of the gastrointestinal tract: clinical and radiographic findings in 11 patients:

Abstract

Aim

To present the gastrointestinal (GI) complications associated with bevacizumab therapy and their findings on abdominal imaging studies.

Methods 

A computerized search identified 11 patients with GI complications of bevacizumab therapy on abdominal CT (n = 11) and fluoroscopic GI contrast studies (n = 4) who met our study criteria (including five patients with ovarian cancer, five with colon cancer, and one with cervical cancer). The medical records and imaging studies were reviewed to determine the clinical and radiographic findings in these patients.

Results  

All 11 patients had findings of GI perforation on CT, or CT and GI contrast studies. CT revealed a localized extraluminal collection containing gas, fluid, and/or contrast material in eight patients (73%) with focal perforation, and free abdominal air and fluid in three (27%) with free perforation The imaging studies also revealed seven fistulas, including two colovaginal, one rectovaginal, one enterocutaneous, one colocutaneous, one gastrocolic, and one colorectal fistula. Eight (73%) of the 11 patients died within 1 year of the development of GI perforation, and the perforation was felt to be the cause of death in four patients (36%).

Conclusion  

Abdominal CT and fluoroscopic GI contrast studies are useful imaging tests for the diagnosis of potentially life-threatening GI perforation as a complication of bevacizumab therapy. When GI perforation is detected on abdominal imaging studies, treatment with bevacizumab should immediately be discontinued.

Complete clinical responses to cancer therapy caused by multiple divergent approaches: a repeating theme lost in translation

Complete clinical responses to cancer therapy caused by multiple diver

Complete clinical responses to cancer therapy caused by multiple divergent approaches: a repeating theme lost in translation (click on 'pdf' for full paper; references to ovarian cancer; hormonal therapy; angiogenesis...)

Abstract:
Over 50 years of cancer therapy history reveals complete clinical responses (CRs) from remarkably divergent forms of therapies (eg, chemotherapy, radiotherapy, surgery, vaccines, autologous cell transfers, cytokines, monoclonal antibodies) for advanced solid malignancies occur with an approximately similar frequency of 5%–10%. This has remained frustratingly almost static. 
However, CRs usually underpin strong durable 5-year patient survival. How can this apparent paradox be explained? 

Single people with cancer often face the toughest battle alone | Health | Macon.com

Single people with cancer often face the toughest battle alone | Health | Macon.com