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open access
History
B.V.
is a 53-year-old nulliparous woman who was initially diagnosed with
recurrent stage 3C epithelial ovarian carcinoma in 2011. She underwent a
hysterectomy, bilateral salpingo-oophorectomy, and optimal tumor
debulking. Adjuvant therapy consisted of a clinical trial (Gynecologic
Oncology Group [GOG] 262) protocol of 6 cycles of IV carboplatin,
paclitaxel, and bevacizumab (Avastin) followed by bevacizumab every 3
weeks.
In 2013, B.V. was diagnosed with invasive
ductal breast cancer, which necessitated discontinuation of bevacizumab
after 12 months of maintenance therapy. She underwent lumpectomy and
adjuvant radiation therapy, which was completed in January 2014. Her
breast tumor was estrogen-/progesterone-receptor (ER/PR) positive. She
was started on tamoxifen.
In February 2014, B.V. had a recurrence of her ovarian cancer......
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