Abstract
BACKGROUND:
Women
with ovarian cancer have a continued high symptom burden in comparison
to other cancer survivors secondary to ongoing chemotherapy treatment.
Prolonged or ineffective management of treatment-related symptoms can
contribute to treatment noncompliance, worsening of symptoms, and
reduced health-related quality of life.
OBJECTIVES:
This
review of the literature was conducted to describe experimental and
quasi-experimental research addressing nonpharmacologic interventions
for the treatment-related symptoms of sleep disturbance, pain, anxiety,
depression, and low energy or fatigue in women with ovarian cancer and
to critique the quality of interventions.
METHODS:
A
systematic search of the literature was conducted in PubMed and yielded
136 articles. Eight articles met the inclusion criteria and were
evaluated.
FINDINGS:
Nonpharmacologic
interventions for treatment-related symptoms were complex, with an
average of 4.4 components. Intervention delivery, setting, and exposure
varied widely across studies. Only three studies contained details
sufficient to replicate the intervention. Lack of clarity in
intervention reporting may explain perceptions of clinically
inefficacious symptom management in this context. Greater attention to
reporting would facilitate better translation of interventions into
practice and when addressing complex cancer symptom clusters.
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