The Risk of Epithelial Ovarian Cancer of Women With Endometriosis May be Varied Greatly if Diagnostic Criteria Are Different

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 The Risk of Epithelial Ovarian Cancer of Women With Endometriosis May be Varied Greatly if Diagnostic Criteria Are Different: A Nationwide Population-Based Cohort Study

 .....The risk of EOC in women with endometriosis varied greatly by different criteria used. Women with endometriosis might have a more apparently higher risk than those reported by systematic review and meta-analysis.
 

INTRODUCTION

Dr. Sampson in 1925 proposed a possible correlation between endometriosis and malignant transformation (occurrence of epithelial ovarian cancer [EOC]); thereafter, many epidemiologic studies, including recent systematic reviews^1–9 and meta-analyses,^3,4,10–12 indicated that women with endometriosis might have an increased risk of EOC. Although epidemiologic studies have not always supported a positive correlation between endometriosis and EOC,^13–15 other studies have reported an unusually high risk of EOC in women with diagnosed endometriosis.^16,17 The question is, why has the risk of EOC in women with endometriosis varied in different studies, ranging from no correlation in Olson study....