Clear cell carcinoma arising in previous episiotomy scar: a case report and review of the literature Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Wednesday, February 10, 2016

Clear cell carcinoma arising in previous episiotomy scar: a case report and review of the literature



open access
 

Background

Malignant transformation of endometriosis associated with episiotomy scar is a rare event, especially histological type of clear cell adenocarcinoma. There are only three clear cell carcinoma in episiotomy scar reported, no standard treatment established.
 

Conclusions

We report a case of clear cell carcinoma arising from episiotomy scar. There are only three clear cell carcinoma in episiotomy scar reported, no standard treatment established. Accumulation of management data on these rare tumors and long-term follow-up of such patients is therefore important.

Case presentation

A 36-year-old woman presented with a two-month history of painless but puritic perineal lump which she noticed was gradually enlarging. The patient’s past gynecological history included frequent vaginitis owing to bad health habits and the lack of professional treatment. Because of discomfort, the patient often scratched the vulva including the lesion of the episiotomy scar for many years. In addition, her past obstetric history was significant. She had a history of a forceps delivery 20 years ago. The postoperative recovery of perineal wound was slow. Several months after delivery, she experienced cyclic perineal pain and swelling of the episiotomy scar. Mifesterone and Medroxyprogesterone acetate injectable suspension (DMPA) were used and the pain was relieved. She had undergone surgical excision of a mass in the episiotomy scar 9 year ago and resequently histological type of endometriosis. DMPA was administrated for one year and then mifesterone for half a year. Medical treatment with Chinese traditional medicine was prescribed after that.....

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