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open access
METHODS
For this prospective cohort study, 55 female patients
were recruited from two cancer treatment centres in Germany and
Switzerland starting in 2013 to the end of 2014. The study was approved
by the corresponding ethics commission (reference no. 01.53.01).
All consecutive cancer patients 18 years of age and
older who planned to undergo neoadjuvant or adjuvant chemotherapy for
breast, endometrial, or ovarian cancer were assessed for enrolment in
the study....CONCLUSIONS
Results from studies of the array of scalp cooling
systems designed to prevent chemotherapy-induced alopecia, a common and
psychologically troubling side effect for cancer patients, have varied.
Our research showed that the effectiveness of DigniCap, a
sensor-controlled scalp cooling system, depends on the chemotherapy
regimen and the patient’s age. Because subjective and objective
indicators of success often differ, we recommend the use of a compound
endpoint to gain more insightful and practical information to use in
counselling patients.
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