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Friday, March 05, 2010

p53 Autoantibodies as Potential Detection and Prognostic Biomarkers in Serous Ovarian Cancer

CONCLUSIONS: Antibodies to p53 are detected in the sera of 42% of patients with advanced serous ovarian cancer.
Impact: Although their utility as a preoperative diagnostic biomarker, beyond CA 125 and HE4, is limited, p53-AAb are prognostic for improved overall survival.
Cancer Epidemiol Biomarkers Prev

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