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Thursday, May 27, 2010

Abstract / full free text: Expression signatures of TP53 mutations in serous ovarian cancers

Conclusions This represents the first attempt to define a genomic signature of TP53 mutation in ovarian cancer. Patterns of gene expression characteristic of TP53 mutation could be discerned and included several genes that are known p53 targets or have been described in the context of expression signatures of TP53 mutation in breast cancer.

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