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Thursday, December 23, 2010
microRNA's - Revolutionizing Ovarian Cancer Treatment
"...That began to change earlier this decade as scientists discovered that microRNAs might actually be the hidden regulators that control the 30,000 genes in the human body by silencing gene expression.....One in particular, miR-31, discovered by Baylor collaborators and
Gunaratne, shows promise as a potent tumor suppressor in ovarian cancer,
glioblastoma, osteosarcoma and prostate cancer.......They discovered that miR-31 can specifically target and kill cancer
cells that are deficient in p53, a crucial gene that guards the
integrity of the genome and prevents cancer. More than half of all
cancers and 90 percent of papillary serous tumors - the most common type
of malignant ovarian cancer - are p53-deficient."
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