BMC Medicine | Abstract/free full text: Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancer (small study)

The complete article is available as a provisional PDF.

Background
About half of Americans 50 to 75 years old do not follow recommended colorectal cancer (CRC) screening guidelines, leaving 40 million individuals unscreened. A simple blood test would increase
screening compliance, promoting early detection and better patient outcomes. The objective of this study is to demonstrate the performance of an improved sensitivity blood-based Septin 9 (SEPT9) methylated
DNA test for colorectal cancer. Study variables include clinical stage, tumor location and histologic grade.