Clinical Oncology News - A Provocative Intersection: Rare cancers, “approved” anti-neoplastics and preclinical models
"Preclinical results
describing a novel approach to the treatment of an uncommon malignant
condition raise a provocative question: How, in the current increasingly
rigid “guideline-based” era of cancer management, can such observations
ever leave the realm of the laboratory to be examined in the clinic?
And can a rational approach to this highly relevant dilemma be devised?
Primary mucinous tumors
comprise a very small proportion (<5%) of morphologic subtypes found
in patients with advanced epithelial ovarian cancer......."
"....One might even argue that
the outcome of such individual non-investigative experiences be posted
in an easily identified, well-organized, condition-specific online
database (with absolutely no accompanying patient-specific identifiers),
so the oncology community would be aware of any clinically beneficial
effects observed if colleagues had previously attempted to employ this
novel approach in an individual patient with a metastatic mucinous
ovarian cancer.....
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