Single antibody shrinks variety of human tumors transplanted into mice, Stanford study shows | e! Science News
Human tumors transplanted into laboratory mice disappeared or shrank
when scientists treated the animals with a single antibody, according to
a new study from the Stanford University School of Medicine. The
antibody works by masking a protein flag on cancer cells that protects
them from macrophages and other cells in the immune system. The
scientists achieved the findings with human breast, ovarian, colon,
bladder, brain, liver and prostate cancer samples. It is the first
antibody treatment shown to be broadly effective against a variety of
human solid tumors, and the dramatic response -- including some overt
cures in the laboratory animals -- has the investigators eager to begin
phase-1 and -2 human clinical trials within the next two years.........
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