Prospective Study of 2-[18F]Fluorodeoxyglucose Positron Emission Tomography in the Assessment of Regional Nodal Spread of Disease in Patients With Breast Cancer: An Ontario Clinical Oncology Group Study
Purpose 2-[18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) is potentially useful in assessing lymph nodes and detecting
distant metastases in women with primary breast cancer.
Conclusion
FDG-PET is not sufficiently sensitive to
detect positive axillary lymph nodes, nor is it sufficiently specific to
appropriately
identify distant metastases. However, the very
high positive predictive value (96%) suggests that PET when positive is
indicative
of disease in axillary nodes, which may
influence surgical care.
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