Gene Maps Are No Cure-All - WSJ.com
"The new study, published Monday in the journal Science Translational
Medicine and presented at a meeting of the American Association for
Cancer Research in Chicago, was based on data from thousands of twins in
five countries. It found that for 23 of 24 diseases analyzed, most
patients would get negative test results, suggesting that their risk of
being stricken with these diseases is low.
In reality, the study says, their risk would be only slightly lower
than that of the general population. Patients who have been
gene-sequenced, particularly without a doctor's counsel, could be lulled
into a false sense of security.....
"For example, one of the diseases studied was ovarian cancer. Dr.
Vogelstein noted that of the 156 million or so women in the U.S., about
2.2 million are expected to get ovarian cancer at some point. But even
if every woman got a whole-genome scan, the tests would be able to
identify only 100,000 of them, Dr. Vogelstein said. "That tells you that
2.1 million women cannot be alerted to the fact that they will get the
cancer," he said......
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