Diabetes mellitus and ovarian cancer: More complex than just increasing risk

abstract

Conclusions

EOC patients with DM have poorer survival than patients without diabetes; this association is independent of obesity. Metformin use did not affect outcomes. The pathophysiology of this observation requires more inquiry.

Highlights

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Diabetes mellitus (DM) is increasingly prevalent in our obese society.

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DM confers poorer outcomes in some cancers, but there is little data regarding its relationship to ovarian cancer.

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DM was associated with worse outcomes regardless of BMI in our population.