Postoperative Adhesions:Impact, Risks, Burden and Complications of Adhesions Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Tuesday, July 12, 2016

Postoperative Adhesions:Impact, Risks, Burden and Complications of Adhesions

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Impact and Burden of Adhesions Following Abdominal Surgery Video Play
Adhesions are fibrous bands of internal scar tissue that can cause tissues and organs that are not otherwise normally connected to stick together.1 Adhesions are the most common and frequent complication of abdominal surgery and form in more than 90% of abdominal surgery patients.1,2

Risks and Complications of Adhesions

Patients with adhesions suffer from major short- and long-term postoperative complications, which place a burden on patients, surgeons, and healthcare systems, including:
  • Small bowel obstruction (SBO)3
  • Female infertility3
  • Chronic abdominopelvic pain3
  • Reoperation for adhesiolysis (surgical removal of adhesions)3
  • Longer operation times and associated increased risk of complications3
  • Limitations on future therapeutic options3
  • Increased mortality risk4,5
While the utmost care can and should be taken during surgery to prevent adhesion formation, adhesions—part of the natural tissue healing process—are not always preventable by surgical technique alone.3,6 While not all adhesions are problematic, many are symptomatic but go undiagnosed as the root cause of comorbidities.3,4
SBO requiring reoperation, caused by a single-band adhesion.

Adhesions: Open Access Articles

Secular trends in small bowel obstruction and adhesiolysis in the United States: 1988–2007

Frank I. Scott, Mark T. Osterman, Najjia N. Mahmoud, James D. Lewis
Background: Postoperative adhesions are common after surgery and can cause small bowel obstruction (SBO) and require adhesiolysis. The impact that laparoscopy and other surgical advances have had on rates of SBO and adhesiolysis remains controversial. This study examines trends in discharges from US hospitals for SBO and adhesiolysis from 1988 to 2007. READ FULL ARTICLE »
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This Postoperative Adhesions Awareness Resource Center is designed to elevate the understanding of the factors involved in post-operative adhesion formation and the serious consequences for patients among healthcare professionals, including surgeons, nurses and physicians assistants, hospital administration and purchasing professionals, and healthcare policy makers. Among the surgical and healthcare planning community, there is a deficit in the comprehension of adhesions and the unfortunate and real impact they have on patient outcomes. This lack of awareness is detrimental to any serious attempt at preventing or minimizing adhesions. On this site, you will find valuable resources, including peer-reviewed articles, presentations, and videos about adhesions and related complications. Please bookmark this page and return for updates.

Healthcare Professional Consultant Disclosures: Since June 2013, Professor Mike Parker has received payments for participation in the following industry initiatives: Symposia (Applied Medical, Covidien, Ethicon Endo Surgery, Sanofi) and Clinical Studies (Carpo Novum).


  1. Sikirica V, Bapat B, Candrill SD, Davis KL, Wilson M, Johns A. The inpatient burden of abdominal and gynecological adhesiolysis in the US. BMC Surg. 2011;11:13.
  2. ten Broek RP, Issa Y, van Santbrink EJ, et al. Burden of adhesions in abdominal and pelvic surgery: systematic review and met-analysis. BMJ. 2013;347:f5588.
  3. Bruggmann D, Tchartchian G, Wallwiener M, Munstedt K, Tinneberg H-R, Hackethal A. Intra-abdominal adhesions. Dtsch Arztebl Int. 2010;107(44):769-775.
  4. DeWilde RL, Trew G; Expert Adhesions Working Party of the European Society of Gynaecological Endoscopy (ESGE). Postoperative abdominal adhesions and their prevention in gynaecological surgery. Expert consensus position. Gynecol Surg. 2007;4:161-168.
  5. van Goor H. Consequences and complications of peritoneal adhesions. J Assoc of Coloproctology of Great Britain and Ireland. 2007;9(suppl 2):25-34.
  6. DeWilde RL, Trew G; Expert Adhesions Working Party of the European Society of Gynaecological Endoscopy (ESGE). Postoperative abdominal adhesions and their prevention in gynaecological surgery. Expert consensus position. Part 2—steps to reduce adhesions. Gynecol Surg. 2007;4:243-253.
Sanofi Biosurgery This Adhesion Awareness Educational Resource Center is sponsored by Sanofi Biosurgery, a Sanofi Company.

The content of this promotional educational site was developed and supported by Sanofi Biosurgery. The opinions expressed here are those of the supporter and do not necessarily reflect the opinions of Elsevier. Use of the Elsevier brand does not constitute a guarantee or endorsement by the company, its journals, associations, or publishers of the quality or value of any products or of any claims made by the manufacturer.

Questions or Comments? Click here to contact Elsevier. Click here to contact Sanofi. This site is intended for non-US Healthcare Professionals.
Copyright © 2016 Elsevier
SAGLB.SEP.14.06.0066 Last Update: December 2014


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