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Sunday, August 21, 2016

Development of ovarian cancer after excision of endometrioma



abstract
 

OBJECTIVE:

To determine the prevalence rate of subsequent development of ovarian cancer after excision of endometrioma.

DESIGN:

Retrospective cross-sectional study.

SETTING:

University hospital.

PATIENT(S):

A total of 485 women with endometrioma.

INTERVENTION(S):

Excisions of endometrioma were performed between 1995 and 2004. Data were collected from medical records in 2013.

MAIN OUTCOME MEASURE(S):

Age, revised American Society for Reproductive Medicine score, cyst diameter, follow-up periods, endometrioma recurrence, and development of ovarian cancer.

RESULT(S):

Recurrence of endometrioma was recorded in 121 patients (24.9% of the entire cohort), and 4 patients (0.8% of the entire cohort) developed ovarian cancer. All ovarian cancers developed from a recurrent endometrioma (3.3% of patients who experienced recurrence). Recurrence of endometrioma was significantly associated with ovarian cancer development.

CONCLUSION(S):

Ovarian cancers can develop after excision of endometrioma and are more likely to arise from recurrent endometrioma. Special care such as rigorous follow-up should be practiced to manage patients who experience recurrence of endometrioma.

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