Identification of therapeutic targets applicable to clinical strategies in ovarian cancer

open access (technical)
August 24, 2016

Table of Contents

• Abstract
• Background
• Methods
• Results
• Discussion
• Conclusions
• Declarations
• References

Conclusions

Loss-of-function screen followed by in vitro target validation using chemical inhibitors identified clinically relevant targets. This approach has the potential to systematically refine therapeutic strategies in OC. These molecular target-driven strategies may provide additional therapeutic options for women whose tumors have become refractory to standard chemotherapy.