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open access
Indeed, many open questions are emerging about the role of BV in OC and many doubts still deserve clear explanations. [77].Should BV be used alone or associated with chemotherapy? Is use of BV as single-agent less toxic in all the patients? Is it extended and maintenance therapy an effective part of front-line treatment?Regarding duration of BV, an extended therapy could be associated with an improved clinical benefit but, at same time, with higher costs and greater toxicity.
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