BRCA Status Does Not Predict Survival for Young Patients With Breast Cancer

BRCA Status Does Not Predict Survival for Young Patients With Breast Cancer - Cancer Therapy Advisor

 The median age of women in the study was 36.

 BRCA1/2 mutation status does not predict survival among young patients, according to findings presented at the 2016 San Antonio Breast Cancer Symposium.¹
 
“There is no significant difference in survival between BRCA gene carriers and non-carriers amongst all young breast cancer patients,” reported Diana Eccles, MD, of the University of Southampton, United Kingdom.

Yet there exists an “11% difference in survival in favor of BRCA carriers who present with triple-negative breast cancer [TNBC],” she added....

Bilateral mastectomy soon after diagnosis does not improve survival among young BRCA mutation carriers, she noted......

 Using clinical genetic services test results and DNA samples tested using a customized breast cancer gene panel, the research team analyzed data for 2759 patients, of whom 379 (approximately 14%) carried BRCA 1 and/or BRCA2 mutations.