BRCA Status Does Not Predict Survival for Young Patients With Breast Cancer Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Monday, December 12, 2016

BRCA Status Does Not Predict Survival for Young Patients With Breast Cancer



BRCA Status Does Not Predict Survival for Young Patients With Breast Cancer - Cancer Therapy Advisor

 The median age of women in the study was 36.

 BRCA1/2 mutation status does not predict survival among young patients, according to findings presented at the 2016 San Antonio Breast Cancer Symposium.1
 
“There is no significant difference in survival between BRCA gene carriers and non-carriers amongst all young breast cancer patients,” reported Diana Eccles, MD, of the University of Southampton, United Kingdom.

Yet there exists an “11% difference in survival in favor of BRCA carriers who present with triple-negative breast cancer [TNBC],” she added....

Bilateral mastectomy soon after diagnosis does not improve survival among young BRCA mutation carriers, she noted......

 Using clinical genetic services test results and DNA samples tested using a customized breast cancer gene panel, the research team analyzed data for 2759 patients, of whom 379 (approximately 14%) carried BRCA 1 and/or BRCA2 mutations.

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