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Lynch syndrome - Genetics Home Reference
Lynch syndrome, often called
hereditary nonpolyposis colorectal cancer (HNPCC), is an inherited
disorder that increases the risk of many types of cancer, particularly (large intestine) and rectum, which are collectively referred to as colorectal cancer. People with Lynch syndrome
also have an increased risk of cancers of the stomach, small intestine,
liver, gallbladder ducts, upper urinary tract, brain, and skin.
Additionally, women with this disorder have a high risk of cancer of the
(the endometrium). People with Lynch syndrome may occasionally have noncancerous (benign) growths (polyps) in the colon, called .
In individuals with this disorder, colon polyps occur earlier but not
in greater numbers than they do in the general population.
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