Special items: Ovarian Cancer and Us blog best viewed in Firefox

▼
Showing posts with label BRCA2. Show all posts
Showing posts with label BRCA2. Show all posts
Thursday, April 12, 2012

open access: A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome - study of 19 BRCA carriers

›
A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome   ".......
1 comment:
Friday, April 06, 2012

BRCA 1/2 Decision Tool - Stanford Medicine Cancer Institute

›
 Blogger's Note: variables can be changed eg. age/prophylactic surgery/s (type), easy to use, tip: hold your cursor over the chart to s...
Wednesday, March 21, 2012

abstract: Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genotype and survival.

›
Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genotype and survival Cancer Genet. 2012 Jan;205(1-2):34-41 Ab...

abstract: DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome (eg. BRCA2, MSH3 (polymorphisms)...)

›
DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome : Source: Cancer Epidemiology, Volume 36, Issue ...
Thursday, March 15, 2012

(click on pdf for full paper) Gynecologic Oncology Case Reports: A Case of Endometrial Cancer in the Context of a BRCA2 Mutation and Double Heterozygosity for Lynch Syndrome

›
Gynecologic Oncology Case Reports | Articles in Press | ScienceDirect.com A Case of Endometrial Cancer in the Context of a BRCA2 Mutati...

abstract: Evaluation of Iniparib as a PARP Inhibitor (BRCA2....)

›
Evaluation of Iniparib as a PARP Inhibitor : Purpose: Poly(ADP-ribose) polymerase (PARP) inhibitors are undergoing extensive clinical te...
Tuesday, September 14, 2010

abstract: 6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance

›
"...Altogether, our data show that 6TG efficiently kills BRCA2-defective tumors and suggest that 6TG may be effective in the treatment ...
Wednesday, September 01, 2010

Preventive Surgeries Linked To Lower Risk Of Breast And Ovarian Cancer - BRCA mutations/international study

›
news article: free full text/paper: http://jama.ama-assn.org/cgi/content/full/304/9/967 "Women who have in herited mutations inth...
Sunday, August 22, 2010

Protein made by breast cancer gene purified - BRCA 2/RAD51

›
Tuesday, August 17, 2010

Identification of a Danish breast/ovarian cancer family double heterozygote for BRCA1 and BRCA2 mutations

›
Abstract Mutations in the two breast cancer susceptibility genes BRCA1 and BRCA2 are associated with increased risk of breast and ovarian ...
Sunday, August 01, 2010

clinical trial: Attitudes About Childbearing And Fertility With Inherited Breast And Ovarian Cancer Syndromes (HBOC) - Full Text View - ClinicalTrials.gov

›
Purpose Objectives: - To evaluate the attitudes and opinions of women undergoing genetic counseling for hereditary breast and ovari...
Saturday, July 24, 2010

International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation

›
"We recommend that all suspected HBOC families from Portugal or with Portuguese ancestry are specifically tested for this rearrangement...
Monday, July 12, 2010

Cancer drug olaparib (PARP inhibitor) shows early promise | Philadelphia Inquirer (BRCA 1/2)

›
Thursday, July 08, 2010

Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer

›
ABSTRACT Purpose The prevalence of BRCA1/2 mutations in germline DNA from unselected ovarian cancer patients is 11% to 15.3%. It is impo...
Wednesday, July 07, 2010

Testing for CHEK2 in the cancer genetics clinic: ready for prime time?

›
Abstract Narod SA. Testing for CHEK2 in the cancer genetics clinic: ready for prime time? The 1100delC mutation of the CHEK2 gene was ...
Friday, May 14, 2010

abstract and free full text: How old is this mutation? - a study of three Ashkenazi Jewish founder mutations

›
The three mutations analyzed were MSH2 *1906 G->C, APC *I1307K, and BRCA2 *6174delT. "Mutation age estimates (averages): 16.8 g...
Thursday, May 13, 2010

Cancer prevalence in 129 breast-ovarian cancer families tested for BRCA1 and BRCA2 mutations (South Africa)

›
Note: small study (Caucasian); stomach cancer link/BRCA2 (?) "Stomach cancer prevalence was significantly elevated in the BRCA2-posi...
Thursday, May 06, 2010

Population-Based Study of the Risk of Second Primary Contralateral Breast Cancer Associated With Carrying a Mutation in BRCA1 or BRCA2 JCO

›
"The risks of subsequent contralateral breast cancer are substantial for women who carry a BRCA1/BRCA2 mutation. These findings have ...
Tuesday, April 27, 2010

Candidate gene association studies: successes and failures

›
Abstract "Epidemiologic studies of twins indicate that 20-40% of common tumors such as breast, colorectal, and prostate cancers are...
Tuesday, April 06, 2010

abstract: Population-Based Study of the Risk of Second Primary Contralateral Breast Cancer Associated With Carrying a Mutation in BRCA1 or BRCA2

›
Results: Compared with noncarriers, BRCA1 and BRCA2 mutation carriers had 4.5-fold (95% CI, 2.8- to 7.1-fold) and 3.4-fold (95% CI, 2.0- to...