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Showing posts with label HE4. Show all posts
Showing posts with label HE4. Show all posts
Sunday, May 27, 2012

Does HE4 have a role in the recurrence of ovarian cancer? | 2012 ASCO Annual Meeting Abstracts (+ links to related ovarian abstracts)

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Does HE4 have a role in the recurrence of ovarian cancer? | 2012 ASCO Annual Meeting Abstracts Abstract: Background: Human epididymis pr...
Thursday, May 17, 2012

paywalled: Two-marker Combinations for Preoperative Discrimination of Benign and Malignant Ovarian Masses

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Two-marker Combinations for Preoperative Discrimination of Benign and Malignant Ovarian Masses Abstract Background:  When caring fo...
Thursday, April 26, 2012

paywalled: Role of HE4, CA72.4, and CA125 in monitoring ovarian cancer.

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Role of HE4, CA72.4, and CA125 in monitoring ovarian cancer . Abstract The aim of this study was to investigate the role of biomark...
Friday, March 30, 2012

abstract: Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders

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Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders : Publication year: 2012 Objective Th...
Wednesday, March 21, 2012

abstract: HE4 combined with MDCT imaging is a good marker in the evaluation of disease extension in advanced epithelial ovarian carcinoma.

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HE4 combined with MDCT imaging is a good marker in the evaluation of disease extension in advanced epithelial ovarian carcinoma Abstract ...
Sunday, March 11, 2012

abstract: Evaluation of ovarian cancer remission markers HE4, MMP7 and Mesothelin by comparison to the established marker CA125 (includes graphic/study of 23 patients)

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 Highlights (in study of 23 patients) ► Three new markers were compared to CA125 for lead time to ovarian cancer recurrence. ► HE4 elevat...
Thursday, March 01, 2012

abstract: Serum HE4 as a diagnostic and prognostic marker for lung cancer (study included ovarian cancer patients)

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Abstract We evaluated the diagnostic and prognostic efficacy of human epididymis protein 4 (HE4) for lung cancer patients by using our n...
Thursday, January 19, 2012

abstract: Reference ranges for HE4 and CA125 in a large Asian population by automated assays and diagnostic performances for ovarian cancer

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"The new automated HE4 assay showed good analytical and diagnostic performances. The reference limits established in our study could ...
Thursday, March 24, 2011

No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting

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of interest : "HE4 was not elevated in endometriosis" CONCLUSIONS: The major advantage of HE4 lies in its specificity and impr...
Saturday, February 12, 2011

abstract: HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm

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Conclusion: This independent validation study demonstrated similar performance indices to those recently published. However, in this study,...
Wednesday, February 09, 2011

The ROMA (Risk of Ovarian Malignancy Algorithm) for estimating the risk of epithelial ovarian cancer in women presenting with pelvic mass: is it really useful? (HE4/CA125/pre-post menopausal)

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Conclusions: The ROMA is a simple scoring system which shows excellent diagnostic performance for the detection of EOC in post-menopausal w...
Thursday, August 12, 2010

Medical News: Cancer Biomarkers Missing in Action - Ovarian Cancer - Medscape

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With a handful of possible exceptions, Diamandis wrote, "very few, if any, molecules have been identified that are expressed only by a...
Sunday, July 04, 2010

HE4 and Mesothelin: Novel Biomarkers of Ovarian Cancer

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"Addition of mesothelin to this combination did not show any improvement in the sensitivity. Conclusions: As a single marker, HE4 had t...
Wednesday, June 16, 2010

full free access: Biomarkers in Medicine - The dire need to develop a clinically validated screening method for the detection of early-stage ovarian

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Note:   I remember the LPA very well ( breakthrough screening test for ovarian cancer and the resulting media hype extraordinaire) Key Exc...
Tuesday, June 15, 2010

p53 autoantibodies as potential detection and prognostic biomarkers in serous ovarian cancer

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IMPACT: Although their utility as a preoperative diagnostic biomarker, beyond CA 125 and HE4, is limited, p53-AAb are prognostic for impr...
Thursday, June 03, 2010

2nd media article: HE4: Abbott gets FDA approval for ovarian cancer test - Chicago Breaking Business

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"Abbott partnered with Fujirebio Diagnostics Inc. to develop the test. It also is approved for use in Europe, and other countries in th...

media article on HE4: FDA approves new test to monitor ovarian cancer

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Tuesday, May 18, 2010

Comparison of a novel multiple marker assay vs the Risk of Malignancy Index for the prediction of epithelial ovarian cancer in patients with a pelvic

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" CONCLUSION : The dual marker algorithm utilizing HE4 and CA125 to calculate a ROMA value achieves a significantly higher sensitivity ...
Thursday, May 13, 2010

Epithelial Ovarian Cancer Clinical Trial: A Trial Using Novel Markers to Predict Malignancy in Elevated-Risk Women [Conditions: Epithelial Ovarian Cancer; Interventions

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Epithelial Ovarian Cancer Clinical Trial: Brief Summary Official Title : “A Randomized Controlled Trial Using Novel ...
Tuesday, April 13, 2010

Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms

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Abstract The HE4 protein is overexpressed in ovarian carcinomas and can be detected in serum by an ELISA with sensitivity similar to CA...