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Showing posts with label PARP inhibitors. Show all posts
Showing posts with label PARP inhibitors. Show all posts
Friday, March 16, 2012

MBCC: PARP Inhibitors for Breast Cancer—Which Subpopulation to Target? - Cancer Network (BRCA, triple-negative breast...)

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MBCC: PARP Inhibitors for Breast Cancer—Which Subpopulation to Target? - Cancer Network "Speaking at the 29th Annual Miami Breast Can...
Thursday, March 15, 2012

abstract: Evaluation of Iniparib as a PARP Inhibitor (BRCA2....)

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Evaluation of Iniparib as a PARP Inhibitor : Purpose: Poly(ADP-ribose) polymerase (PARP) inhibitors are undergoing extensive clinical te...
Thursday, March 08, 2012

March 7th /text and/or podcast: PARP Inhibitors and the Challenges of Developing Ovarian Cancer Therapeutics - Cancer Network Dr's Ledermann/Birrer

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Blogger's Note: podcast and/or text available, registration required (free)                           ~~~~~~~~~~~~~~~~~~ PARP Inhibi...

open access: Nature Reviews: Key Advances in Medicine - Ovarian Cancer/Markman page 15-16

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Key Advances in Medicine (book) Nature Reviews Clinical Oncology  (page 15)S11 ovarian cancer | Mutations and non-inferiority analyses s...
Thursday, February 09, 2012

Feb 9th: The Maze of PARP Inhibitors in Ovarian Cancer - Cancer Network

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Blogger's Note:  full access, free subscription Conclusion "While consideration of chemoprevention with PARP inhibitors is on t...
Tuesday, June 28, 2011

media: (PARP inhibitors) Researchers: Breast Cancer Drug May Treat Other Cancers

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Monday, April 25, 2011

medical news: New Class of Cancer Drugs Could Work in Colon Cancers with Genetic Mutation (PARP inhibitors/MRE11 gene/Lynch Synrome))

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15% of colorectal cancers have mutation that responds to PARP inhibitors Newswise — ANN ARBOR, Mich. — A class of drugs that shows promis...
Monday, March 28, 2011

PARP Inhibitor Active in Ovarian Cancer (preliminary studies MK4827) upload date March 22nd

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Monday, November 15, 2010

New test for ovarian cancer patients - RAD51 assay (UK)

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Note: search blog for additional RAD51 information/studies
Tuesday, September 14, 2010

abstract: 6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance

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"...Altogether, our data show that 6TG efficiently kills BRCA2-defective tumors and suggest that 6TG may be effective in the treatment ...
Tuesday, July 20, 2010

abstract: Cochrane Collaboration review: DNA-repair pathway inhibitors for the treatment of ovarian cancer (PARP inhibitors)

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"Our objective was to compare effectiveness and side effects of PARP inhibitors compared to conventional chemotherapy in women with ov...
Thursday, July 08, 2010

Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer

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ABSTRACT Purpose The prevalence of BRCA1/2 mutations in germline DNA from unselected ovarian cancer patients is 11% to 15.3%. It is impo...
Friday, June 25, 2010

research: BRCA-Negative Ovarian Cancer Responds to Monotherapy With PARP Inhibitor | Cancer Survivors Network

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Note: detailed article on PARP's/BRCA "....Interest in PARP inhibition was perhaps best reflected by the question an attendee at t...
Saturday, June 19, 2010

Clinical Care Options Oncology - Slideset: Research Update on PARP Inhibition: Emerging Data in Breast, Ovarian, and Other Cancers

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Source: Research Update on PARP Inhibition: Emerging Data in Breast, Ovarian, and Other Cancers William J. Gradishar, MD, FACP, reviews t...
Saturday, May 08, 2010

Clinical Care Options Oncology - Research Update on PARP Inhibition: Emerging Data in Breast, Ovarian, and Other Cancers - Virtual Presentation

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Note:   free access/register Research Update on PARP Inhibition: Emerging Data in Breast, Ovarian, and Other Cancers Interactiv...