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Showing posts with label phase 1. Show all posts
Showing posts with label phase 1. Show all posts
Saturday, May 05, 2012

EphA2 Gene Targeting Using Neutral Liposomal Small Interfering RNA Delivery - Full Text View - ClinicalTrials.gov Phase 1 solid tumors

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EphA2 Gene Targeting Using Neutral Liposomal Small Interfering RNA Delivery - Full Text View - ClinicalTrials.gov Official Title: ...
Thursday, April 19, 2012

Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancer - Full Text View - ClinicalTrials.gov

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Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancer - Full Text View - ClinicalTrials.gov ...
Tuesday, April 17, 2012

financial news: ImmunoGen Says IND For Anticancer Compound IMGN853 Is Now Active

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ImmunoGen Says IND For Anticancer Compound IMGN853 Is Now Active (RTTNews.com) - ImmunoGen, Inc. ( IMGN ) announced that the Investigati...
Saturday, March 17, 2012

abstract: Phase I trial of intraperitoneal pemetrexed, cisplatin, and paclitaxel in optimally debulked ovarian cancer.

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Phase I trial of intraperitoneal pemetrexed, cisplatin, and paclitaxel in optimally debulked ovarian cancer. Abstract PURPOSE:...
Monday, March 12, 2012

Phase 1 - TKM 080301 for Primary or Secondary Liver Cancer - Full Text View - ClinicalTrials.gov (ovariancolorectal/pancreas/gastric (stomach)/breast)

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TKM 080301 for Primary or Secondary Liver Cancer - Full Text View - ClinicalTrials.gov Colorectal Cancer With Hepatic Metastases ...
Wednesday, March 07, 2012

DPX-Survivac vaccine - Biotech company raises $2.8 million for R&D | The Chronicle Herald

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"Halifax biotechnology company Immunovaccine Inc. has raised $2.8 million in equity funding that will help the company push forward wi...
Friday, February 17, 2012

abstract: Phase I clinical and pharmacokinetic study of trabectedin and carboplatin in patients with advanced solid tumors (including OC)

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Phase I clinical and pharmacokinetic study of trabectedin and carboplatin in patients with advanced solid tumors. Investigational new Drug...
Tuesday, February 07, 2012

abstract: A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas (brca/triple negative bc)

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CONCLUSIONS: The combination of veliparib with metronomic cyclophosphamide is well tolerated and shows promising activity in a subset of...
Thursday, February 02, 2012

not yet recruiting - Phase 1 Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors - Full Text View - ClinicalTrials.gov

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Wednesday, April 13, 2011

UK phase 1 - ADZ5363 - New cancer drug to be tested by patients - Business News - Healthcare Digital

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"Medication that prevents the enzyme, Protein Kinase B (PKB), has the potential to treat breast cancer , prostate cancer , ovarian canc...
Monday, February 28, 2011

full free access (pdf): A phase I study with an expanded cohort to assess the feasibility of intraperitoneal carboplatin and intravenous paclitaxel in untreated ovarian, fallopian tube, and primary peritoneal carcinoma: A Gynecologic Oncology Group study

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Research Highlights ► The MTD (maxium tolerated dose) of IP carboplatin with IV paclitaxel (175 mg/m 2 ) was an AUC 8. ►IP carboplatin can...
Sunday, November 14, 2010

Phase 1/pharmacology study of intraperitoneal topotecan alone and with cisplatin: potential for consolidation in ovarian cancer.

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Thursday, October 07, 2010

Phase I Study of Vorinostat in Patients With Advanced Solid Tumors and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study — JCO

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Note: abstract does not indicate if ovarian cancer patients were included in this phase 1 study
Tuesday, June 15, 2010

First-in-human trial of a poly(ADP-ribose) polymerase (PARP) inhibitor MK-4827 in advanced cancer patients (pts) with antitumor activity in BRCA-deficient and sporadic ovarian cancers (phase 1)

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Results: 39 pts (male 10, female 29; median age 58 years; 11 BRCA mutation carriers) were treated... Conclusions: MK-4827 is well toler...
Wednesday, May 12, 2010

Phase I clinical trials in 85 patients with gynecologic cancer: The M. D. Anderson Cancer Center experience

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Note: the abstract does not detail outcomes/disease specific sites
Thursday, May 06, 2010

med blog: You Shouldn't Call Something a Breakthrough When It's in a Phase I Trial

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Tuesday, April 27, 2010

MLN8237 in Patients With Ovarian, Fallopian Tube or Peritoneal Cancer Preceded by Phase 1 Study of MLN8237 Plus Paclitaxel Treatment of Ovary or Breast Cancer

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Saturday, April 17, 2010

Intensity-modulated whole abdominal radiotherapy after surgery and carboplatin/taxane chemotherapy for advanced ovarian cancer: phase I study

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CONCLUSIONS: The results of this Phase I study showed for the first time, to our knowledge, the clinical feasibility of intensity-modulated...
Monday, April 05, 2010

utube - Deborah Armstrong, MD, Johns Hopkins Kimmel Cancer Center, discusses Early studies of enzastaurin and bevacizumab.SGO

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free full access: A phase-I trial of pemetrexed plus carboplatin in recurrent ovarian cancer.

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for full free access click on 'pdf'