OVARIAN CANCER and US

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Monday, January 12, 2009

Diagnostic experience among 4,334 women reporting surgically diagnosed endometriosis



"...Sometime before diagnosis, 63% were told nothing was wrong with them."

(Editorial note: since there is a known connection between endometrioid and clear cell ovarian cancer cell types to endometriosis, it would be interesting to note followup on those subsequently diagnosed not only with endometriosis but also with ovarian cancer)

OEDC 2008 Renumeration of General Practitioners and Specialists in 14 OECD Countries



41925333.pdf (application/pdf Object)

The government’s role in health care | Health Innovation Forum



The government’s role in health care | Health Innovation Forum

"More importantly, after nearly 30 years of overt attempts to manage provincial systems, they are still not stable or sustainable. This worrisome outcome results from the convergence of three probably uncontrollable and partially self-imposed factors I like to call the “Bermuda Triangle” of health care."

Women at High Risk for Breast Cancer--What the Primary Care Provider Needs to Know



Women at High Risk for Breast Cancer--What the Primary Care Provider Needs to Know -- Afonso 22 (1): 43 -- The Journal of the American Board of Family Medicine

Sunday, January 11, 2009

Disease without boundaries



Disease without boundaries

Sarcomas associated with hereditary nonpolyposis cancer (Lynch Syndrome): broad anatomical and morphological spectrum



Sarcomas associated with hereditary nonpolyposis c...[Fam Cancer. 2009] - PubMed Result

TheStar.com - Sick Kids loses top-paid fundraisers



TheStar.com | News & Features | Sick Kids loses top-paid fundraisers

Toronto Star: Disclose Charity Pay



Disclose charity pay
January 11, 2009

In these tough times, Canadian charities are working harder than ever to raise money for their good works.

But for charities, as for any business, it costs money to raise money.

To help maintain public confidence in charity work, the Canada Revenue Agency regulates fundraising by requiring the disclosure of what percentage of donations is spent on administration costs. Under proposed CRA guidelines released last year, charities should keep fundraising costs below 35 cents on the dollar. The goal is to reassure donors that most of their money is going to help deserving causes, rather than paying expenses and salaries.

Yet Ottawa is still lagging behind the U.S. in its regulation of the vital fundraising sector.

As the Star's Kevin Donovan reminded us in his recent story about a change of the guard at one of Toronto's biggest charities, most fundraisers won't say how much money they are paying their own top people. He reported that the departing president of SickKids Foundation, Michael O'Mahoney, earned a remarkable $624,103 in salary and benefits last year, more than the president of the Hospital for Sick Children for which he was raising money.

The Star discovered O'Mahoney's salary only because of disclosure documents filed with the Internal Revenue Service in the U.S., where SickKids Foundation arm does business, not the CRA.

Canada had long lagged behind the U.S. in disclosure of corporate salaries but, belatedly, shone a light on something shareholders have every right to know. Fundraising has become a big business, and the donors who have a stake in Canada's 83,000 charities deserve no less transparency than shareholders in big corporations.



The standardized live patient and mechanical patient models - their roles in trauma teaching



The standardized live patient and mechanical patie...[J Trauma. 2009] - PubMed Result

The clonal evolution of metastases from primary serous epithelial ovarian cancers



The clonal evolution of metastases from primary se...[Int J Cancer. 2008] - PubMed Result

Increased ovarian cancer risk associated with menopausal estrogen therapy is reduced by adding a progestin



Increased ovarian cancer risk associated with meno...[Cancer. 2009] - PubMed Result

Peritoneal carcinomatosis: patients selection, perioperative complications and QOL related to cytoreductive surgery and hyperthermic IP chemo HIPEC



1477-7819-7-5.pdf (application/pdf Object)

Critical Care Canada Forum



Critical Care Canada Forum

Presentations

* 'Substitute Decision Making: Conflicts and Controversies in Practice' by Mark Handelman (Flash Movie)
* 'Unilateral Withdrawal: An 11th Commandment?' by Anand Kumar (Flash Movie)
* 'When is Enough Enough? An Ethical Perspective' by Robert Sibbald (Flash Movie)
* 'Legal Framework & Cases Affecting Critical Care in Ontario' by Joan Gilmour (Flash Movie)

Thursday, January 08, 2009

CSDH Conference 2008 video: Health as a Human Right (a Human Rights Report)



CSDH Conference

global inequality and discrimination and poverty - Universal Declaration of Human Rights

NEJM -- Communicating Medical News -- Pitfalls of Health Care Journalism



NEJM -- Communicating Medical News -- Pitfalls of Health Care Journalism

Readers as research detectives abstract + free full text



Abstract | Readers as research detectives

"Commentary - Readers as research detectives

Peter C Gøtzsche

Trials 2009, 10:2doi:10.1186/1745-6215-10-2
Published: 7 January 2009
Abstract (provisional)

Flaws in research papers are common but it may require arduous detective work to unravel them. Checklists are helpful, but many inconsistencies will only be revealed through repeated cross-checks of every little detail, just like in a crime case. As a major deterrent for dishonesty, raw data from all trials should be posted on a public website. This would also make it much easier to detect errors and flaws in publications, and it would allow many research projects to be performed without collecting new data. The prevailing culture of secrecy and ownership to data is not in the best interests of the patients."

Wednesday, January 07, 2009

Monday, January 05, 2009

European Journal of Human Genetics - Breast cancer susceptibility genes analysed into three groups: Genomics and breast cancer: the different levels of inherited susceptibility



European Journal of Human Genetics - Breast cancer susceptibility genes analysed into three groups: Genomics and breast cancer: the different levels of inherited susceptibility

Cytoreductive surgery for recurrent ovarian cancer: A meta-analysis



Conclusions

Among patients undergoing operative intervention for recurrent ovarian cancer, the proportion of patients undergoing complete cytoreductive surgery is independently associated with overall post-recurrence survival time. For this select group of patients, the surgical objective should be resection of all macroscopic disease.

Part II: Liver Function in Oncology: Towards Safer Chemotherapy Use



Part II: Liver Function in Oncology: Towards Safer Chemotherapy Use - OncologySTAT

Vitamins, Micronutrients, and Cancer Prevention: Where Do We Stand? - Editorial



Vitamins, Micronutrients, and Cancer Prevention: Where Do We Stand? - OncologySTAT

Hormone Replacement Therapy Virtual Symposium (Slides With Audio)



Hormone Replacement Therapy Virtual Symposium (Slides With Audio)

Doctors don't own medical knowledge --- Canadian Medical Association Journal



Doctors don't own medical knowledge -- El Halim 180 (1): 140 -- Canadian Medical Association Journal

Medical errors, apologies and apology laws --- Canadian Medical Association Journal



Medical errors, apologies and apology laws -- MacDonald and Attaran 180 (1): 11 -- Canadian Medical Association Journal

Central East LHIN (Ontario)- Integration-Process slide/pdf file



Integration-Process_for_website.pdf (application/pdf Object)

There is no requirement of the LHIN or HSP provider to conduct a community engagement process

The cancer survival gap between elderly and middle-aged patients in Europe is widening



The cancer survival gap between elderly and middle-aged patients in Europe is widening

Incidence of Ovarian, Peritoneal, and Fallopian Tube Carcinomas in the United States, 1995-2004



Incidence of Ovarian, Peritoneal, and Fallopian Tube Carcinomas in the United States, 1995-2004 -- Goodman and Shvetsov 18 (1): 132 -- Cancer Epidemiology Biomarkers & Prevention

Position Paper ComplementaryTherapies



PositionPaper_ComplementaryTherapies.pdf (application/pdf Object)

Conference abstracts of a new oncology drug do not always lead to full publication: Proceed with caution



ScienceDirect - Journal of Clinical Epidemiology : Conference abstracts of a new oncology drug do not always lead to full publication: Proceed with caution

Sunday, January 04, 2009

P.O.V. - In the Family | PBS short video (genetics)



P.O.V. - In the Family | PBS

A phase 2 trial of oral Imatinib in patients with epithelial ovarian, fallopian tube, or peritoneal carcinoma in second or greater remission.



A phase 2 trial of oral imatinib in patients with ...[Eur J Gynaecol Oncol. 2008] - PubMed Result

Tragic results of suboptimal gynecologic cancer operations



Tragic results of suboptimal gynecologic cancer op...[Eur J Gynaecol Oncol. 2008] - PubMed Result


"CONCLUSION: If a gynecologist does not have enough experience or expertise about gynecological cancer operations, he or she must consider the possible harm that any surgical intervention might do, as the latin phrase 'primum non nocere' means and should refer patients to a gynecological oncology center without performing any surgery."

Prospective study of physical activity and the risk of ovarian cancer



Prospective study of physical activity and the ris...[Cancer Causes Control. 2008] - PubMed Result

"CONCLUSIONS: Neither moderate nor vigorous physical activity showed a statistically significant association with ovarian cancer in this large cohort of women."

Consideration of hereditary nonpolyposis colorectal cancer (HNPCC/Lynch Syndrome) in BRCA mutation negative familial ovarian cancers



Consideration of hereditary nonpolyposis colorecta...[Cancer. 2008] - PubMed Result

"CONCLUSIONS:: HNPCC should be considered when evaluating patients with suspected hereditary ovarian cancer who have had negative BRCA mutation testing"

Clinical trials in Canada: whose interests are paramount?



Clinical trials in Canada: whose interests are par...[Int J Health Serv. 2008] - PubMed Result

Clinical trials in Canada: whose interests are paramount?

Lexchin J. School of Health Policy and Management, York University, Toronto, ON, Canada. jlexchin@yorku.ca

More than 80 percent of clinical drug trials in Canada are funded by the pharmaceutical industry. This article evaluates the overall state of clinical trials in Canada and looks at the interplay between public and private interests. Health Canada has adopted standards developed by the International Conference on Harmonization, a body that is heavily influenced by industry. Commercial interests are increasingly involved in recruiting patients into clinical trials and in running these trials. It is in industry's interests to conduct drug tests on people for which it is easiest to see benefits. These interests are not fundamentally challenged by Health Canada's policy of issuing nonmandatory guidelines on who should and should not be included in clinical trials. The outcome of clinical trials is heavily influenced by commercial sponsorship, with the result that trials may favor corporate interests rather than the interests of the public. How Health Canada deals with that possibility is not known, because of its strict policy of treating clinical trial data as private property. If clinical trials are to serve the purpose for which they are designed, developing reliable and objective information about new drugs, then commercial interests cannot be allowed to take precedence over health interests.

Chromosome 8q23.3 and 11q23.1 Variants Modify Colorectal Cancer Risk in Lynch Syndrome



Chromosome 8q23.3 and 11q23.1 Variants Modify Colorectal Cancer Risk in Lynch Syndrome

A Limited Panel of Immunomarkers Can Reliably Distinguish Between Clear Cell and High-grade Serous Carcinoma



The American Journal of Surgical Pathology - Abstract: Volume 33(1) January 2009 p 14-21 A Limited Panel of Immunomarkers Can Reliably Distinguish Between Clear Cell and High-grade Serous Carcinoma

Medical students' experiences with addicted patients: a web-based survey



Medical students' experiences with addicted patien...[Subst Abus. 2008] - PubMed Result

"Students reacted strongly to the psychosocial impact of addictions on patients, yet they viewed addiction as a personal choice, not an illness. Conclusion: Medical students are not being trained to diagnose addiction or provide advice and counseling. Medical schools need to provide students with positive clinical experiences supervised by physicians experienced in addictions."

Predictors of Referral for Specialized Psychosocial Oncology Care in Patients With Metastatic Cancer: The Contributions of Age, Distress, and Marital



Predictors of Referral for Specialized Psychosocia...[J Clin Oncol. 2008] - PubMed Result

YouTube - Transcending: Words on Women and Strength by Kelly Corrigan



YouTube - Transcending: Words on Women and Strength by Kelly Corrigan

http://tinyurl.com/6kqqhg

Saturday, January 03, 2009

Love As A Found Object - daughter's blog: "So. How's cancer going?"



Love As A Found Object

"'So. How's cancer going"

Division of Gynecologic Oncology: U of Toronto - application



ApplForm_08.pdf (application/pdf Object)

Planning and implementing a collaborative clinical placement for medical, nursing and allied health students: a qualitative study



Planning and implementing a collaborative clinical...[Med Teach. 2008] - PubMed Result

Management of melanomas of the female genital tract



Management of melanomas of the female genital trac...[Curr Opin Oncol. 2008] - PubMed Result

A serum based analysis of ovarian epithelial tumorigenesis



A serum based analysis of ovarian epithelial tumor...[Gynecol Oncol. 2009] - PubMed Result

Can the preoperative Ca-125 level predict optimal cytoreduction in patients with advanced ovarian carcinoma? A single institution cohort study



Can the preoperative Ca-125 level predict optimal ...[Gynecol Oncol. 2009] - PubMed Result: "Can the preoperative Ca-125 level predict optimal cytoreduction in patients with advanced ovarian carcinoma? A single institution cohort study"

A contemporary analysis of ability of pre-op serum CA-125 to predict primary cytoreductive outcome in patients advanced ovarian, tubal & peritoneal



A contemporary analysis of the ability of preopera...[Gynecol Oncol. 2009] - PubMed Result

"A contemporary analysis of the ability of preoperative serum CA-125 to predict primary cytoreductive outcome in patients with advanced ovarian, tubal and peritoneal carcinoma"