OVARIAN CANCER and US

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Saturday, November 14, 2009

2009 Yi & St Louis Ovarian Cancer Montage at OneTrueMedia.com



Updated photos including Montage of 2008 Special Ovarian Cancer Womens' Montage

A Survey Of Primary Care Physicians In Eleven Countries, 2009: Perspectives On Care, Costs, And Experiences -- Schoen et al. 28 (6): w1171 -- Health Affairs



Cost Effectiveness and Resource Allocation | Full text | Can economic evaluation of telemedicine be trusted? A systematic review of the literature



Trends in cancer incidence and mortality in Osaka, Japan: Evaluation of cancer control activities



Risk of gynecological cancers in users of estradiol/dydrogesterone or other HRT preparations.



Tissue-Selective Regulation of Aromatase Expression by Calcitriol: Implications for Breast Cancer Therapy.



Women’s Decision Making about Risk-Reducing Strategies in the Context of Hereditary Breast and Ovarian Cancer



Genetic Counselors’ Religiosity & Spirituality: Are Genetic Counselors Different from the General Population?



partial view: Recontacting Patients Who have Tested Negative for BRCA1 and BRCA2 Mutations: How, Who and Why?



partial view: Response - Response to Robert G. Resta Commentary (Unprepared, Understaffed, and Unplanned: Thoughts on the Practical Implications of Di



Response to Robert G. Resta Commentary (Unprepared, Understaffed, and Unplanned: Thoughts on the Practical Implications of Discovering New Breast and Ovarian Cancer Causing Genes

Forty Years' War - Medicines to Deter Some Cancers Are Not Taken - Series - NYTimes.com



Forty Years' War - Medicines to Deter Some Cancers Are Not Taken - Series - NYTimes.com

preview: Unprepared, Understaffed, and Unplanned: Thoughts on the Practical Implications of Discovering New Breast and Ovarian Cancer Causing Genes




Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor



Serum estradiol should be monitored not only during the peri-menopausal
period but also the post-menopausal period at the time of aromatase inhibitor
administration

Australia: lEffects & feasibility of a multi-disciplinary orientation program for newly registered cancer patients



Abstract | Effects and feasibility of a multi-disciplinary orientation program for newly registered cancer patients: design of a randomised controlled trial

Malignant struma ovarii: an analysis of 88 cases, including 27 with extraovarian spread




Monday, November 09, 2009

Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin.




Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines




Current state of biomarker development for clinical application in epithelial ovarian cancer.



Gynecol Oncol. 2009 Oct 29
Current state of biomarker development for clinical application in epithelial ovarian cancer.

Moore RG, Maclaughlan S, Bast RC Jr.
Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital, Alpert Medical School, Brown University, Providence, RI, USA.


Each year in the United States over 15,000 women die of epithelial ovarian cancer (EOC) and 22,000 are diagnosed with the disease. The incidence of ovarian cancer has remained stable over the past decade however, survival rates have improved steadily. Increases in survival rates can be attributed to the advances in surgical management, development of effective cytotoxic drugs and the route of administration of chemotherapy. Ovarian cancer survival rates could also be improved through screening and early detection. Disappointingly, effective screening methods have not been established and continue to be elusive. Historically the goal of a screening test was to achieve a positive predictive value (PPV) greater than 10% in order be considered cost effective and have an acceptable risk for the population being screened. Despite the inability of currently available screening algorithms to achieve the desired PPV there may be an advantage in producing a stage migration to lower stages at the time of diagnoses, thereby resulting in improved survival. Equally important recent studies have demonstrated that women who have their initial surgery performed by gynecologic oncologists, and women who have their surgeries at centers experienced in the treatment of ovarian cancer have higher survival rates. For these reasons it is essential that all women at high risk for ovarian cancer receive their initial care by gynecologic oncologists and at centers with multidisciplinary teams experienced in the optimal care of ovarian cancer patients. With this in mind, methods that facilitate the accurate triage of women who will ultimately be diagnosed with ovarian cancer could play a significant role in improving survival rates for these patients. This review article will examine the current state of biomarker use in ovarian cancer screening, risk assessment and for monitoring ovarian cancer patients.

Association of pegylated liposomal doxorubicin and ifosfamide in early recurrent ovarian cancer patients: A Multicenter Phase II Trial



Clinical Cancer Advances 2009: Major Research Advances in Cancer Treatment, Prevention, and Screening - ASCO



Clinical Activity of Gemcitabine Plus Pertuzumab in Platinum-Resistant Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer -- Makhija et al., 10.1200/JCO.2009.22.3354 -- Journal of Clinical Oncology



Estrogens, MSI and Lynch syndrome-associated tumors



Qualitative exploration of healthcare relationships following delayed diagnosis of ovarian cancer and subsequent participation in supportive-expressiv



Qualitative exploration of healthcare relationships following delayed diagnosis of ovarian cancer and subsequent participation in supportive-expressive group therapy

Ovarian Cancer Update: Lessons From Morphology, Molecules, and Mice



Ovarian Cancer Update: Lessons From Morphology, Molecules, and Mice

NCI - new series: Coping with Cancer - Supportive and Palliative Care




CancerView.ca - search results - NIL



Canadian Partnership Against Cancer and affiliate:

Search Results:
SAGE

Target Population -
Age: Adult
Continuum Of Care: Treatment
Type of Cancer: Gynecology



No results found to display

Body mass index as a prognostic factor in epithelial ovarian cancer and correlation with clinico-pathological factors



Conclusion. Overweight and obese patients did not have worse survival than normal weight and underweight patients. The prognostic impact of BMI on survival was only noted for underweight patients with serous tumors.

Long-term meat intake and risk of breast cancer by oestrogen and progesterone receptor status in a cohort of Swedish women



QUOTE chemo: A patient-centred instrument to measure quality of communication preceding chemotherapy treatment through the patient’s eyes



QUOTE: Odd how the p in patients' is in small caps ??

Preventing Future Cancers by Testing Women With Ovarian Cancer for BRCA Mutations -- Kwon et al., 10.1200/JCO.2008.21.4684 -- Journal of Clinical Oncology




Friday, November 06, 2009

Treatment decision making and its discontents



Soc Work Health Care. 2009 Aug-Sep;48(6):614-34.
Treatment decision making and its discontents.

Sinding C, Wiernikowski J.

Department of Health, Aging, and Society, and School of Social Work, McMaster University, Hamilton, Ontario, Canada. sinding@mcmaster.ca

Patient participation in treatment decision making is held as a virtue in clinical contexts, and has much to recommend it. Yet important questions have been raised about the assumptions underlying models of patient participation. Debates have arisen about the significance of medically defined risks and outcomes of treatment; the adequacy and relevance across social groups of the concept of autonomy; and the emphasis on the professional-patient dyad. This article contributes to the debate about treatment decision making with reference to a study focused on older women with cancer. Interviews with patients and cancer care professionals highlighted the salience to patients' treatment choices of experiential knowledge, social roles and responsibilities, and the health policy context. It appears that prevailing models of decision making may obscure patients' more typical decision processes as well as the social determinants of those choices.

The Contents and Readability of Informed Consent Forms for Oncology Clinical Trials



CONCLUSIONS:: ICF had acceptable readability and provided a realistic overview of the benefits and risks of clinical trials, but the potential for hospitalization or fatality was underreported.

Thursday, November 05, 2009

Update: H1N1 and Cancer



A miracle. Our ovarian cancer friend is now in the hospital and receiving the care that she feels she needs and which she deserves. A good news story!

Wednesday, November 04, 2009

What You Don’t Know Might Kill You



Why a Top Cancer Center Could Save Your Life | Newsweek Health | Newsweek.com

Unbearability of suffering at the end of life: the development of a new measuring device, the SOS-V



Unbearability of suffering at the end of life: the development of a new measuring device

Update - from Nov 3rd - Letter to the Editor H1N1 and Cancer (ovarian cancer woman in need)



Editor's Comment: I received this response and have forwarded the information on to my ovarian cancer friend. It was sent onwards (obviously). One small step and although only the friend herself will know if this will be helpful, it is one small step.
Sandi

Dear Ms. Pnaiuskas, can you forward to her the information that I sent you yesterday?  She can also contact me directly.

Thanks,

BC Cancer Agency WebQueries
 604-675-8005     604-675-8009 
 1-888-675-8000, local 8005
* 675 West 10th Avenue
    Vancouver, BC  V5Z 1L3

Sunday, November 01, 2009

H1N1 and Cancer - update



Letter to the Editor;


With the focus of attention on H1N1 are we allowing care for those 
desparately ill to go to the bottom of today's priority list? It would 
seem so. 

I have a friend in need. The cancer is killing both of us. The 
cancer is killing my friend because of the disease. It is killing me 
because I am sitting here watching and listening to this friend who 
needs help but cannot access palliative care assistance. It seems that 
this patient has tried to access help without success. 

I believe there must be a healthcare provider somewhere in this province, 
who can exercise some form of a miracle and connect the dots. Out of privacy 
concerns I will not publicly provide this patient's personal information 
but what I do need is someone in the Vancouver area who has the authority, 
ability and willingness to help this patient. 

As a cancer survivour and friend, the best I can do is place a call for action. 
As a healthcare provider, you have the means to make it work. I will connect 
you. Please help because we need to and we must.

Sandi Pniauskas

October 30, 2009

http://ovariancancerandus.blogspot.com
http://ovariancancerdebate.blogspot.com/

November 1st, 2009 update: This letter was circulated through 
media outlets, Twitter, Facebook,
listservs, professional organizations etc. With the exception
of Charles Adler (media broadcaster) 
and 2 cancer survivours it fell on deaf ears.


Initial evaluation and referral guidelines for management of pelvic/ovarian masses - Canada



"Patients deemed to have a high risk of an underlying malignancy should be reviewed in consultation with a gynaecologic oncologist for assessment and optimal surgical management."

Who are the providers of gynaecologic cancer surgical care in Ontario?



"CONCLUSION: Gynaecologists perform over half of the operations for gynaecologic cancers in Ontario."

Laparoscopic peritoneal entry preferences among Canadian gynaecologists



Abstract: the response rate to the survey was 45.6%

"CONCLUSIONS: Our survey had a significant response rate and was able to delineate current laparoscopic entry practice patterns of gynaecologists, which were consistent across Canada. Despite 72.9% of respondents reporting familiarity with the recent SOGC clinical practice guideline, it appears that clinical practice does not necessarily coincide with current recommendations. These variances in gynaecological practice emphasize the need for further educational initiatives to ensure that the evidence from research is used to make clinical practice safer."

Malignant Ascites Symptom Cluster in Patients Referred for Paracentesis.



The contribution of founder mutations to early-onset breast cancer in French-Canadian women