OVARIAN CANCER and US

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Sunday, October 26, 2008

click here to view: Recap of 4 related items - Ovarian Cancer Screening/Diagnostic Markers





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LETTERS TO THE EDITOR:
Diagnostic Markers for Ovarian Cancer Screening: Not Ready for Routine Clinical Use
Ralph J. Coates, Katherine Kolor, Sherri L. Stewart, and Lisa C. Richardson
Clin. Cancer Res., Oct 2008; 10.1158/1078-0432.CCR-08-2296.
Abstract
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... ...Editor Diagnostic Markers for Ovarian Cancer Screening: Not Ready for Routine...of women who are diagnosed with ovarian cancer each year (1) and the poor survival...of a serum biomarker test for ovarian cancer with a reported sensitivity of... ...

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LETTERS TO THE EDITOR:
The Importance of Test Positive Predictive Value in Ovarian Cancer Screening
Mark H. Greene, Ziding Feng, and Mitchell H. Gail
Clin. Cancer Res., Oct 2008; 10.1158/1078-0432.CCR-08-2232.
Abstract
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... ...Test Positive Predictive Value in Ovarian Cancer Screening Mark H. Greene Ziding...immunoassay system as a candidate for ovarian cancer screening in high-risk populations...has recently been marketed as an ovarian cancer screening test by LabCorp, under... ...

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LETTERS TO THE EDITOR:
Ovarian Cancer Early Detection Claims Are Biased
Martin McIntosh, Garnet Anderson, Charles Drescher, Samir Hanash, Nicole Urban, Pat Brown, Sanjiv Sam Gambhir, George Coukos, Peter W. Laird, Brad Nelson, and Chana Palmer
Clin. Cancer Res., Oct 2008; 10.1158/1078-0432.CCR-08-0623.
Abstract
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... ...Letters to the Editor Ovarian Cancer Early Detection Claims Are Biased...1) claim the ability to detect ovarian cancer early and with 95.3% sensitivity...used to compare the plasma from ovarian cancer cases and healthy controls. Specimens... ...

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LETTERS TO THE EDITOR:
In Response
Gil Mor, Peter E. Schwartz, and Herbert Yu
Clin. Cancer Res., Oct 2008; 10.1158/1078-0432.CCR-08-2621.
Abstract
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... ...markers for the early detection of ovarian cancer," and an erratum table published...population based on the incidence of ovarian cancer in the general population, which...Yale Early Detection Program for Ovarian Cancer in the Department of Obstetrics... ...

Gardasil Passes a 2-Year Safety Check



Gardasil Passes a 2-Year Safety Check:
"Most parents' concerns about Gardasil were not explicitly related to concerns about vaccine safety."

The Lancet Oncology - World Cancer Declaration (needs password - free - to view)



The Lancet Oncology

Reflection and Reaction

World Cancer Declaration: a need for partnership

"We can no longer afford to sit on our hands and watch people die needlessly. We all have a personal and common responsibility to help overcome this global challenge and I encourage you to read the World Cancer Declaration, endorse the policy via the UICC website, and think carefully about what changes you can do, however small, in your private and professional lives to bring about change, before we live to regret this moment in history."



The Lancet Oncology - The Ideal Pleurodesis Agent: still searching after all of these years (requires password - free - to view)



The Lancet Oncology

2008 Health Care in Canada - full report (103 pages)



HCIC_2008_e.pdf (application/pdf Object)
Health Care in Canada 2008 (HCIC 2008) is the ninth in a series of annual
reports on the health care system and the health of Canadians. This year,
HCIC 2008 provides a review of key analytic work undertaken at CIHI that
highlights CIHI’s health care research priorities (access, quality of care, costs,
health human resources and population mental health). Also included in this
report are key findings from seminal Canadian and international health care
research as they relate to these health care priorities. HCIC 2008 is a reference
tool to identify current priorities in health care for health researchers, persons
involved in strategic decision-making in health care, the media and Canadians
in general.

Low grade serous ovarian cancer: a unique disease



HighWire Press -- Medline Abstract

link to 4 articles re: diagnostic markers discussion ovarian cancer




In Response - Mor et al



Letters to the Editor Ovarian Cancer Early Detection Claims Are Biased



Letters to the Editor Diagnostic Markers for Ovarian Cancer Screening: Not Ready for Routine Clinical Use



Letters to the Editor The Importance of Test Positive Predictive Value in Ovarian Cancer Screening




God Syndrome | Psychology Today Blogs



God Syndrome | Psychology Today Blogs: "Medicine is a complex affair; we frequently do not do justice to what our patients suffer and what they need."

Thursday, October 23, 2008

news item: Gates Foundation Awards $100,000 grants (non-peer review)



Flying Syringes and Other Bold Ideas - washingtonpost.com

"In making its picks, the foundation has rejected the widespread practice of peer review -- assigning other specialists in a field to evaluate research -- because, in the words of Tadataka Yamada, the foundation's director of global health, "peer review -- by definition almost -- excludes innovation because innovation has no peers."

Thursday, October 16, 2008

British Journal of Cancer - Survival from cancer of the ovary in England and Wales up to 2001



British Journal of Cancer - Survival from cancer of the ovary in England and Wales up to 2001

The Cochrane Collaboration - Multimedia from the Plenaries at the XIV Cochrane Colloquium in Freiburg, Germany, October 2008



The Cochrane Collaboration - Multimedia from the Plenaries at the XIV Cochrane Colloquium in Freiburg, Germany, October 2008

TheStar.com | Federal Election | Health policy debate fizzles despite Canadians' priorities



"Canadians are justly proud of their health system but this election campaign does not mirror their concerns,"

TheStar.com | Federal Election | Health policy debate fizzles despite Canadians' priorities

"So, are you back to work yet?" Re-conceptualizing 'work' and 'return to work' - abstract



"So, are you back to work yet?" Re-conceptualizing...[Soc Sci Med. 2008] - PubMed Result


"..When patients return for surgical follow up, clinicians routinely ask, "So, are you back to work yet?" expecting simple 'yes/no' answers.

This study suggests that the answer is instead highly complex, and that patients could be seen as having been 'working' all along. This study offers a re-conceptualization of 'work' and 'return to work'....."

Tuesday, October 14, 2008

Gynecologic Cancer - ASCO 2008 sundry presentations/videos



Gynecologic Cancer - ASCO

Assessment and Prevention of Hereditary Ovarian Cancer - ASCO 2008 slides/videos



Assessment and Prevention of Hereditary Ovarian Cancer - ASCO

Gynecologic Cancer Track - ASCO 2008 slides/videos



Gynecologic Cancer Track - ASCO

Pivotal Evaluation of the Accuracy of a Biomarker Used for Classification or Prediction: Standards for Study Design --JNCI



Pivotal Evaluation of the Accuracy of a Biomarker Used for Classification or Prediction: Standards for Study Design -- Pepe et al. 100 (20): 1432 -- JNCI Journal of the National Cancer Insti

The Process to Discover and Develop Biomarkers for Cancer: A Work in Progress -- Journal of the National Cancer Institute



The Process to Discover and Develop Biomarkers for Cancer: A Work in Progress -- Ransohoff 100 (20): 1419 -- JNCI Journal of the National Cancer Institute

2008 GLOBAL VOLUNTEER MANAGEMENT SURVEY



0805GLOBALVOLUNTEERMANAGEMENTSURVEYDRAFT6.pdf (application/pdf Object)

Sunday, October 12, 2008

Measuring the impact of patient and public involvement: the need for an evidence base -- Staniszewska et al., 10.1093/intqhc/mzn044 -- International Journal for Quality in Health Care



Measuring the impact of patient and public involvement: the need for an evidence base -- Staniszewska et al., 10.1093/intqhc/mzn044 -- International Journal for Quality in Health Care

Coordinated prophylactic surgical management for women with hereditary breast-ovarian cancer syndrome



BioMed Central | Full text | Coordinated prophylactic surgical management for women with hereditary breast-ovarian cancer syndrome:
"Although we did not have any substantial complications associated with the gynecologic surgery in our series, there is a potential risk in adding the gynecologic procedure to prophylactic surgery, especially in the setting of autologous reconstructive surgery."

2008 Coordinated prophylactic surgical management for women with hereditary breast-ovarian cancer syndrome



BioMed Central | Full text | Coordinated prophylactic surgical management for women with hereditary breast-ovarian cancer syndrome

2008 Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a Clinical Cancer Genetics service setting



Research article Open Access

Penetrance estimates for BRCA1 and BRCA2 based on genetic
testing in a Clinical Cancer Genetics service setting: Risks of
breast/ovarian cancer quoted should reflect the cancer burden in
the family

1471-2407-8-155.pdf (application/pdf Object)