Wednesday, August 29, 2012
Tuesday, August 28, 2012
Non-adherence patient care.......
"....Non-adherence is a problem but it is not the patient's problem. It is really an indication that something has gone wrong in the process of delivering care..."
http://www.google.ca/reader/i/?source=mog&hl=en&gl=ca#stream/feed%2Fhttp%3A%2F%2Fwww.cancerworld.org%2Ffeed.html
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Recommendations for including multiple symptoms as endpoints in cancer clinical trials - 2012 - Cancer
Recommendations for including multiple symptoms as endpoints in cancer clinical trials
A report from the ASCPRO (Assessing the Symptoms of Cancer Using Patient-Reported Outcomes) Multisymptom Task Force
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BRAF Mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer - Grisham - 2012 - Cancer - Wiley Online Library
Original Article
BRAF Mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer
Article first published online: 28 AUG 2012
DOI: 10.1002/cncr.27782
Copyright © 2012 American Cancer Society
Issue
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Mandated "GMO Food" Disclosure: Labeling for Thee but Not for Me - Forbes
Labeling for products that meet the USDA-NOP standards (Photo credit: Wikipedia)
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Journal of Oncology Practice-Do High Symptom Scores Trigger Clinical Actions? An Audit After Implementing Electronic Symptom Screening
Do High Symptom Scores Trigger Clinical Actions? An Audit After Implementing Electronic Symptom Screening
- Hsien Seow, PhD,
- Jonathan Sussman, MD, MSc,
- Lorraine Martelli-Reid, RN, MN, NP,
- Greg Pond, PhD, PStat and
- Daryl Bainbridge, PhD
- Corresponding author: Hsien Seow, PhD, Cancer Care Ontario Research Chair in Health Services Research, Assistant Professor, Department of Oncology, McMaster University, 699 Concession St, 4th floor, Rm 4-229, Hamilton, Ontario L8V 5C2, Canada; e-mail: seowh@mcmaster.ca.
Abstract
Purpose: Standardized, electronic, symptom assessment is purported to help identify symptom needs. However, little research examines clinical processes related to symptom management, such as whether patients with worsening symptoms receive clinical actions more often. This study examined whether patient visits with higher symptom scores are associated with higher rates of symptom documentation in the chart and symptom-specific actions being taken.
Methods: Retrospective chart reviews on cancer patient visits at a regional cancer center. An electronic Edmonton Symptom Assessment Scale (ESAS), a validated tool to measure symptoms, was implemented center-wide to standardize symptom screening at every patient visit. The independent variable was ESAS scores for pain and shortness of breath, categorized by severity: 0 (none), 1-3, 4-6, 7-10 (severe). Outcomes included symptom documentation in the chart on the visit date and symptom-related action(s) taken within 1 week.
Results: Nine hundred twelve visits were identified. Pain and shortness of breath were documented in 51.8% and 29.7% of charts, and a related-action occurred in 16.9% and 3.9% of charts, respectively. As ESAS severity score category increased from none to severe, the proportion of visits with pain documented increased significantly (36.9%, 49.2%, 55.2%, and 71.4%; P < .001). Likewise, as ESAS score severity increased, the proportion of visits with a pain-related action increased significantly (4.2%, 10.6%, 21.3%, and 37.0%; P < .001). Trends were similar for shortness of breath.
Conclusion: Results show a positive association between higher symptom scores and higher rates of documentation and clinical actions taken. However, symptom-related actions were documented in a minority of visits in which symptoms were noted as severe.
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JOP : Journal of Oncology Practice - patient/physician discussions regarding cancer costs (abstract)
"Conclusion: Patients' comfort with and desire to discuss cancer costs exceed that of oncologists, suggesting a need to educate oncologists on this important topic. A patient's desire to understand treatment-associated cost does not equate with a desire for cost to influence medical decision making."
http://m.jop.ascopubs.org/content/8/4/e50.short?rss=1
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Journal of negative results article
During an interview with Journal of Negative Results in BioMedicine (JNRBM), Dr Haiko Sprott(below) provides some interesting and thought-provoking views on why the publication of negative results is valuable to the scientific community. Dr Sprott is Head of the Pain Clinic Basel, Switzerland, and carries out research into chronic pain, pain genes and multimodal pain therapy. He is also an Editorial Board member forJNRBM.
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Trials-open access journal
Trials is an open access, peer-reviewed, online journal that encompasses all aspects of the performance and findings of randomized controlled trials. We publish articles on general trial methodology as well as protocols, commentaries and traditional results papers - regardless of outcome or significance of findings.
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Monday, August 27, 2012
CancerConnect Live Web Chat with Dr. Chi and Dr. Bell-McGuinn from Memorial Sloan-Kettering Cancer Center on Treatment Options for Ovarian Cancer on September 24, 2012 at 7:00pm EST : CancerConnect News
CancerConnect Live Web Chat with Dr. Chi and Dr. Bell-McGuinn from Memorial Sloan-Kettering Cancer Center on Treatment Options for Ovarian Cancer on September 24, 2012 at 7:00pm EST
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Unexpected findings at multi-detector CT scans: Less reason to worry
Unexpected Findings at Multi-Detector CT Scans: Less Reason to Worry
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The Autophagy Protein LC3A Correlates with Hypoxia and is a Prognostic Marker of Patient Survival in Clear Cell Ovarian
Original Paper
The Autophagy Protein LC3A Correlates with Hypoxia and is a Prognostic Marker of Patient Survival in Clear Cell Ovarian Cancer
Issue
The Journal of Pathology
Sunday, August 26, 2012
Ann_Oncology - Preoperative PET/CT in early-stage breast cancer
Preoperative PET/CT in early-stage breast cancer
Abstract
Background The aim of this study was to assess the diagnostic and therapeutic impact of preoperative positron emission tomography and computed tomography (PET/CT) in the initial staging of patients with early-stage breast cancer.
Patients and methods A total of 103 consecutive patients with newly diagnosed operable breast cancer with tumors ≥2 cm were independently examined preoperatively with conventional assessment (mammography, breast/axillary ultrasound, chest X-ray and blood samples) and PET/CT with no prior knowledge of the other.
Results PET/CT identified a primary tumor in all but three patients (97%). PET/CT solely detected distant metastases (ovary, bones and lung) in 6 patients and new primary cancers (ovary, lung) in another two patients, as well as 12 cases of extra-axillary lymph node involvement. In 15 patients (15%), extra-axillary malignancy was detected by PET/CT only, leading to an upgrade of initial staging in 14% (14/103) and ultimately a modification of planned treatment in 8% (8/103) of patients.......,
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Saturday, August 25, 2012
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