Saturday, January 31, 2009
Genetic classification of ovarian carcinoma based on microsatellite analysis: Relationship to clinicopathological features and patient survival
abstract:
Genetic classification of ovarian carcinoma based on microsatellite analysis: Relationship to clinicopathological features and patient survival
These findings suggest that some ovarian carcinomas have a significant degree of overlap between the two pathways of genomic instability and that the genetic classification using microsatellite markers may represent a potential new biomarker of risk prediction in ovarian carcinoma.
Distribution of microsatellite instability in Danish ovarian tumor patients and the prognositic value in ovarian cancer patients
Distribution of microsatellite instability in Dani...[Oncol Res. 2008] - PubMed Result
In conclusion, we found no association to any of the clinical parameters evaluated, although a tendency of a higher frequency of MSI was observed among serous OC.
Systematic Review and Meta-analysis of Ovarian Cancers: Estimation of Microsatellite-High Frequency and Characterization of Mismatch Repair Deficient Tumor Histology
abstract:
Systematic Review and Meta-analysis of Ovarian Cancers: Estimation of Microsatellite-High Frequency and Characterization of Mismatch Repair Deficient Tumor Histology -- Pal et al. 14 (21): 6847 -- C
The frequency of the MSI-H phenotype in unselected ovarian cancers approximates 12%. MMR-deficient ovarian cancers also seem to be characterized by an overrepresentation of nonserous histologic subtypes. Knowledge of histologic subtype may aid clinicians in identifying the relatively large proportion of ovarian cancers due to MMR defects; such knowledge has potential implications for medical management.
Friday, January 30, 2009
Thursday, January 29, 2009
news article: Self-diagnosis can be risky - Dee Williams/ACOR ovarian listserv
Self-diagnosis can be risky | courier-journal | The Courier-Journal
"And she's found camaraderie by connecting with other ovarian cancer patients through such sites as The Association of Cancer Online Resources.
'The ovarian list is very active,' she said. 'Every day there's probably at least 50-60 posts. Someone will say, 'Hey, I'm starting this chemo treatment. What can you tell me about it?' and women will reply, 'Oh, I've been on it and it made me sick,' or 'It gave me diarrhea.' '
Women from inside and outside the United States participate, sometimes sharing journal articles and recommending doctors to each other, in addition to offering support, Edwards said.
Thanks to them, she said, 'I feel like I have a local support group and then I have my global support group' on the Internet."
Hanging in the Balance: Making Decisions About the Benefits and Harms of Breast Cancer Screening Among the Oldest Old Without a Safety Net of Scientific Evidence
Hanging in the Balance: Making Decisions About the Benefits and Harms of Breast Cancer Screening Among the Oldest Old Without a Safety Net of Scientific Evidence -- Mandelblatt and Silliman 27
Editorial:
"Aside from the acknowledged methodological caveats and the potentially misleading press surrounding the article by Badgwell et al,5 the study's investigators and the Journal of Clinical Oncology are to be commended for raising difficult questions in gero-oncology, especially when the answers are imperfect. The intensity about the controversy that followed this publication reflects the fact that we are ill-prepared from a scientific knowledge perspective to provide health care rationally, ethically, equitably, and humanely to the 'booming' older population."
When Informed, All Women Do Not Prefer Breast Conservation
When Informed, All Women Do Not Prefer Breast Conservation -- Throckmorton and Esserman 27 (4): 484 -- Journal of Clinical Oncology
The key to offering a choice is respecting the choices patients make. Some people will choose one path, others a different one. We need to accept that women will have different values and want different choices. Our job should be to make sure patients have the choices, the information, the time, and environment in which to make an informed, value-driven decision.
Should patient-rated performance status affect treatment decisions - ECOG score
PS=performance status
Should patient-rated performance status affect tre...[J Thorac Oncol. 2008] - PubMed Result
"CONCLUSIONS: Pt-PS and MD-PS were not congruent in over half of the cases, with Pt-PS scores usually poorer. Almost half the patients would have excluded themselves from a hypothetical clinical trial (Pt-PS >/=2). This requires prospective evaluation."
Wednesday, January 28, 2009
Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers
note: Table 4 does not include self image etc in gyn cancers but does in breast cancer
Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers -- Rebbeck et al. 101 (2): 80 -- JNCI Journal of the National Cancer
Tuesday, January 27, 2009
Monday, January 26, 2009
HE4 Test with CA125 for Risk Stratification of Women with Suspected Ovarian Cancer
Pivotal Data Published For First Biomarker Combination Test to Determine Risk of Ovarian Cancer in Women Who Present With Pelvic Mass
ZAIDA - Caring Bridge journal
(Posted with permission of Mom): Zaida (ZAY-da) turned 4 in September. We learned she has cancer on 10/31/07, after six very emotional days in the hospital. Two days later we learned it was ovarian cancer. More recently, the diagnosis is mesothelioma of the peritoneum, with an ovarian promotor.
Older Patients and the Shifting Focus of Cancer Care
Older Patients and the Shifting Focus of Cancer Care - Cancer Network
"Conclusions
Society has treated elderly cancer patients poorly, even in cases where curative therapy exists."
Sunday, January 25, 2009
Diversity of participants in clinical trials in an academic medical center
Wiley InterScience :: JOURNALS :: Cancer
Further research also should consider whether differentially recruiting
good patients
can impact the ethnic/racial diversity or other characteristics of trial participants in ways that may bias the outcomes or conclusions of therapeutic trials.
Friday, January 23, 2009
webcast presentation: Menopause and Osteoporosis | January 22, 2009 | Media Advisories | Media Centre | SOGC
Prevalence, distress, management, and relief of pain during the last 3 months of cancer patients' life - Italian mortality follow-back survey
Annals of Oncology Advance Access published online on January 22, 2009
Annals of Oncology, doi:10.1093/annonc/mdn700
| |
Prevalence, distress, management, and relief of pain during the last 3 months of cancer patients' life. Results of an Italian mortality follow-back survey
1 Regional Palliative Care Network, National Cancer Research Institute, Genoa
2 Palliative Care Unit, IRCCS Foundation, National Cancer Institute, Milan
3 Department of Epidemiology, National Cancer Research Institute, G. Pascale Foundation, Naples
4 ASP Lazio, Rome
5 Liguria Cancer Registry, Descriptive Epidemiology, National Cancer Research Institute, Genoa
6 Clinical Epidemiology, Center for the Study and Prevention of Cancer, Florence, Italy
* Correspondence to: Dr M. Costantini, Regional Palliative Care Network, National Cancer Research Institute, Largo R. Benzi, 10 16132 Genova, Italy. Tel: +39-010-5737482; Fax: +39-010-354103; E-mail: massimo.costantini@istge.it
Background: This study estimates prevalence, management, and relief of pain during the last 3 months of life of a representative sample of dying cancer patients in Italy.
Patients and methods: This is a mortality followback survey (the Italian Survey of the Dying of Cancer). Caregivers were interviewed, after the patient's death, about pain experienced by the patients in all settings of care.
Results: According to caregivers' reports, 82.3% [95% confidence interval (CI) 79.9% to 84.4%] patients experienced pain, and 61.0% (95% CI 57.9% to 64.0%) very distressing pain. The younger population experienced a higher prevalence of pain in respect to older patients (P <> central nervous system experienced the lowest prevalence (51.9%). According to caregivers' reports, only 59.5% (95% CI 3.7% to 65.0%) received analgesic treatment with opioids for moderate to severe pain. Not surprisingly, pain was ‘only partially relieved’ or ‘not relieved at all’ in 54% of the patients with very distressing pain.
Conclusions: Although potentially slightly biased, the results from this survey regarding undermedication and poor treatment results for cancer related pain are unequivocal. The research agenda should focus on testing the effectiveness of interventions to improve the quality of pain assessment and management.
cancer, effectiveness, opioids, pain, prevalence, treatment
Received for publication March 25, 2008. Revision received August 1, 2008. Accepted for publication October 7, 2008.
Thursday, January 22, 2009
Canada NewsWire Group
Canada NewsWire Group: "The webcast will explain key findings from the clinical review, with a focus on hormone therapy, osteoporosis, cardiac health and cognitive function.'"
The effect of obesity on survival in patients with ovarian cancer
Conclusion
Although obesity has been reported as an independent prognostic factor for survival, this data demonstrates that survival rates are similar between obese and non-obese patients when optimal debulking statuses are the same. Therefore, maximal effort should be directed towards optimal debulking obese patients with EOC.
Wednesday, January 21, 2009
Tuesday, January 20, 2009
Monday, January 19, 2009
Information exchange between provider and patient -- Brown 180 (2): 207 -- Canadian Medical Association Journal
Information exchange between provider and patient -- Brown 180 (2): 207 -- Canadian Medical Association Journal
"Emerging technologies such as patient-accessible electronic health records should be considered as a means of facilitating the transmission of information not only between providers but also between provider and patient to address gaps in the continuity of care."
CDC Issues Cancer Genetic Test Recommendations | GenomeWeb
CDC Issues Cancer Genetic Test Recommendations | GenomeWeb
"After conducting an evidence-based analysis, the CDC's Evaluation of Genomic Applications in Practice and Prevention Working Group, or EWG, said it could recommend offering genetic testing for Lynch syndrome to newly diagnosed colorectal cancer patients, but that it did not find enough evidence to recommend for or against two other types of genetic tests, for breast cancer and metastatic colorectal cancer."
Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers -- Rebbeck et al., 10.1093/jnci/djn442 -- JNCI Journal of the National
Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers -- Rebbeck et al., 10.1093/jnci/djn442 -- JNCI Journal of the National
In conclusion, the summary risk reduction estimates presented here confirm that BRCA1/2 mutation carriers who have been treated with RRSO have a substantially reduced risk of both breast and ovarian cancer. However, residual cancer risk remains after surgery. Therefore, additional cancer risk reduction and screening strategies are required to maximally reduce cancer incidence and mortality in this high-risk population.
The HPV Vaccine Controversy
The HPV Vaccine Controversy
"Gardasil was fast-tracked and received FDA approval before its final safety evaluation trials were complete, and its final safety evaluation trials won’g be concluded until September 2009. Despite this, the drug is being aggressively mass-marketed on TV and at the movies in adverts pitched to young girls, including preteens, and state legislators were heavily lobbied to make the drug mandatory for school girls ages 11 and up. Parents are understandably reluctant to give the shots to daughters who are not yet sexually active, and the long-term impacts of which are entirely unknown."
Sunday, January 18, 2009
Awards of excellence 2008 CANO: Pamela J. West
Awards of excellence
CANO/NOCA Award for Excellence in Gynecology-Oncology Nursing
Previous recipients of this award include:
2008 Pamela West
2007 Lynne Jolicoeur
2006 Joanne Brodeur
Australia What changes are needed to the current direction and interpretation of clinical cancer research to meet the needs of the 21st century?
Abstract
In this 21st century, we will need to better analyse the outcomes of our spending on newer and more expensive anticancer drugs, particularly through postmarketing assessment, to ensure that these investments are justified.
Evidence-based medicine is only as good as the evidence available, and we advocate for more independently designed and funded trials that concentrate on the minimum effective dose and duration of therapies to reduce toxicity to patients and to control costs. There is a place for governments to provide funding for these studies in the public good.
Although improving survival over standard care is the gold standard for proving the efficacy of a new therapy, surrogate endpoints such as early biological marker changes, functional imaging changes or earlier measures such as progression-free survival must be investigated to enable drug therapies to be discontinued earlier if they are ineffective.
Studies searching for the presence of biological targets must be funded to exploit the potential advantage of targeted therapies.
Treatment guidelines are best written by experts who are independent of the pharmaceutical industry.
Existing databases should be linked to better monitor the outcomes of new therapies. Privacy safeguards are important, but privacy legislation may need to be modified to serve the greater public good from the information gained from linking databases.
Friday, January 16, 2009
Medical News: Final Medicare Rule Shuts Off Payment for Erroneous Surgeries
Medical News: Final Medicare Rule Shuts Off Payment for Erroneous Surgeries - in Geriatrics, Medicare from MedPage Today
"The surgical mistakes join 12 categories of errors and preventable complications already on the CMS blacklist, which went into effect on Oct. 1:
* Objects left in after surgery
* Air embolisms
* Blood incompatibility
* Pressure ulcers
* Falls in the hospital
* Catheter-associated urinary tract infections
* Catheter-associated vascular infections
* Mediastinitis after CABG
* Inadequate glycemic control
* Surgical site infections
* Deep vein thrombosis and pulmonary embolism
* Drug-induced delirium
For those 12 errors, however, CMS is denying claims only for hospital inpatient reimbursements."
Thursday, January 15, 2009
Wednesday, January 14, 2009
Clinical Patterns and Biological Correlates of Cognitive Dysfunction Associated with Cancer Therapy
Clinical Patterns and Biological Correlates of Cognitive Dysfunction Associated with Cancer Therapy -- Dietrich et al. 13 (12): 1285 -- The Oncologist
ABSTRACT
Standard oncological therapies, such as chemotherapy and cranial radiotherapy, frequently result in a spectrum of neurocognitive deficits that includes impaired learning, memory, attention, and speed of information processing. In addition to classical mechanisms of neurotoxicity associated with chemo- and radiotherapy, such as radiation necrosis and leukoencephalopathy, damage to dynamic progenitor cell populations in the brain is emerging as an important etiologic factor. Radiation- and chemotherapy-induced damage to progenitor populations responsible for maintenance of white matter integrity and adult hippocampal neurogenesis is now believed to play a major role in the neurocognitive impairment many cancer survivors experience.
Tuesday, January 13, 2009
18F-FDG PET and PET/CT in the Evaluation of Cancer Treatment Response - The Journal of Nuclear Medicine
18F-FDG PET and PET/CT in the Evaluation of Cancer Treatment Response -- Ben-Haim and Ell 50 (1): 88 -- The Journal of Nuclear Medicine
Note: Ovarian Cancer is discussed under the Miscellaneous section.
WHI Participant website
WHI Participant website
January 2009 New results from the Women’s Health Initiative Memory Study of Magnetic Resonance Imaging (WHIMS-MRI)
Monday, January 12, 2009
The effect of obesity on survival in patients with ovarian cancer (repost from 2008)
Conclusion
Although obesity has been reported as an independent prognostic factor for survival, this data demonstrates that survival rates are similar between obese and non-obese patients when optimal debulking statuses are the same. Therefore, maximal effort should be directed towards optimal debulking obese patients with EOC.
news item: Colonoscopy Fails to Identify Many Colorectal Cancers
Daily Cancer News - CancerConsultants.com
While researchers have long estimated that colonoscopy reduces colorectal cancer deaths by 90%, the results of this analysis indicate that the reduction might be closer to 60%. More research is needed to understand the implications of this analysis. In the meantime the researchers caution that the results of this study should not change the colonoscopy screening recommendations. A 60% reduction in mortality is still an important benefit; in comparison, mammography reduces breast cancer mortality by only 25%.
Globe and Mail: 2 articles: Obesity and Ovarian Cancer and McHealth stories leave us all hungry
globesports.com: McHealth stories leave us all hungry
Media articles of interest:In fact, the paper Body Mass Index and Risk of Ovarian Cancer (2009 American Cancer Society/Cancer Journal) as published:
Obesity / Ovarian cancer article: http://tinyurl.com/9ak8st
McHealth stories: http://tinyurl.com/7xmwsf
My online response as below: http://tinyurl.com/9554b6
(S Pniauskas, from Canada) wrote:
A prime example of the ethical, moral and professional duty of apparent
medical reporting is Andre's recent article: "Obesity raises risk of ovarian cancer".
"Conclusions: Based on the results of the current study, the authors SUSPECT that obesity....As observed in numerous previous investigations summarized in a recent meta-analysis of the available literature, BMI at baseline was associated with a modest but statistically NONSIGNIFICANT INCREASE IN RISK for ovarian cancer in our cohort as a whole... "
The whole article in the Globe regarding Obesity and Risk of Ovarian Cancer is significantly pathetic including the fact that the last sentence regarding risk of recurrence/higher rate of death is not accurate. What is accurate is the fact that if chemotherapy treatments are given according to BMI then the risk is Nil.
Ovarian Cancer and most cancers cannot simply be explained away by simple one page articles and to try to do so places additional burdens on our populations which are in fact fighting for and often losing the challenge of trying to live with life threatening cancers. Research communities publish their work as a 'work in progress' and not as the final solution to extremely complicated issues. Many factors influence the onset and risk of ovarian and other cancers and we simply are not there yet in understanding the full implications of any particular one or two potential issues.
It is an old lesson yet learned that medical reporting has a duty to understand the full context of the issues, as well as a duty to do no harm, which is not exclusively held to medical professionals but to also to medical reporting.
There are educational courses available to medical journalists and consumers, one being through the Cochrane Collaboration.
Diagnostic experience among 4,334 women reporting surgically diagnosed endometriosis
"...Sometime before diagnosis, 63% were told nothing was wrong with them."
(Editorial note: since there is a known connection between endometrioid and clear cell ovarian cancer cell types to endometriosis, it would be interesting to note followup on those subsequently diagnosed not only with endometriosis but also with ovarian cancer)
The government’s role in health care | Health Innovation Forum
The government’s role in health care | Health Innovation Forum
"More importantly, after nearly 30 years of overt attempts to manage provincial systems, they are still not stable or sustainable. This worrisome outcome results from the convergence of three probably uncontrollable and partially self-imposed factors I like to call the “Bermuda Triangle” of health care."
Sunday, January 11, 2009
Toronto Star: Disclose Charity Pay
Disclose charity pay
January 11, 2009
In these tough times, Canadian charities are working harder than ever to raise money for their good works.
But for charities, as for any business, it costs money to raise money.
To help maintain public confidence in charity work, the Canada Revenue Agency regulates fundraising by requiring the disclosure of what percentage of donations is spent on administration costs. Under proposed CRA guidelines released last year, charities should keep fundraising costs below 35 cents on the dollar. The goal is to reassure donors that most of their money is going to help deserving causes, rather than paying expenses and salaries.
Yet Ottawa is still lagging behind the U.S. in its regulation of the vital fundraising sector.
As the Star's Kevin Donovan reminded us in his recent story about a change of the guard at one of Toronto's biggest charities, most fundraisers won't say how much money they are paying their own top people. He reported that the departing president of SickKids Foundation, Michael O'Mahoney, earned a remarkable $624,103 in salary and benefits last year, more than the president of the Hospital for Sick Children for which he was raising money.
The Star discovered O'Mahoney's salary only because of disclosure documents filed with the Internal Revenue Service in the U.S., where SickKids Foundation arm does business, not the CRA.
Canada had long lagged behind the U.S. in disclosure of corporate salaries but, belatedly, shone a light on something shareholders have every right to know. Fundraising has become a big business, and the donors who have a stake in Canada's 83,000 charities deserve no less transparency than shareholders in big corporations.
Critical Care Canada Forum
Critical Care Canada Forum
Presentations
* 'Substitute Decision Making: Conflicts and Controversies in Practice' by Mark Handelman (Flash Movie)
* 'Unilateral Withdrawal: An 11th Commandment?' by Anand Kumar (Flash Movie)
* 'When is Enough Enough? An Ethical Perspective' by Robert Sibbald (Flash Movie)
* 'Legal Framework & Cases Affecting Critical Care in Ontario' by Joan Gilmour (Flash Movie)
Saturday, January 10, 2009
Journal of Ovarian Research | Full text | Can Subjective Global Assessment of Nutritional Status Predict Survival in Ovarian Cancer?
Journal of Ovarian Research | Full text | Can Subjective Global Assessment of Nutritional Status Predict Survival in Ovarian Cancer?
"Background
Malnutrition is a significant problem in patients with ovarian cancer. The goal of this study was to investigate the prognostic role of Subjective Global Assessment (SGA) in patients with ovarian cancer treated in an integrative cancer treatment setting."
Thursday, January 08, 2009
CSDH Conference 2008 video: Health as a Human Right (a Human Rights Report)
CSDH Conference
global inequality and discrimination and poverty - Universal Declaration of Human Rights
Readers as research detectives abstract + free full text
Abstract | Readers as research detectives
"Commentary - Readers as research detectives
Peter C Gøtzsche
Trials 2009, 10:2doi:10.1186/1745-6215-10-2
Published: 7 January 2009
Abstract (provisional)
Flaws in research papers are common but it may require arduous detective work to unravel them. Checklists are helpful, but many inconsistencies will only be revealed through repeated cross-checks of every little detail, just like in a crime case. As a major deterrent for dishonesty, raw data from all trials should be posted on a public website. This would also make it much easier to detect errors and flaws in publications, and it would allow many research projects to be performed without collecting new data. The prevailing culture of secrecy and ownership to data is not in the best interests of the patients."
Wednesday, January 07, 2009
Dietary patterns and ovarian cancer risk -- Kolahdooz et al. 89 (1): 297 -- American Journal of Clinical Nutrition
Dietary patterns and ovarian cancer risk -- Kolahdooz et al. 89 (1): 297 -- American Journal of Clinical Nutrition
"Conclusions: A diet characterized by high meat and fat intake may increase the risk of epithelial ovarian cancer. A diet high in fruit and vegetables was not associated with reduced risk."
Tuesday, January 06, 2009
Monday, January 05, 2009
Cytoreductive surgery for recurrent ovarian cancer: A meta-analysis
Conclusions
Among patients undergoing operative intervention for recurrent ovarian cancer, the proportion of patients undergoing complete cytoreductive surgery is independently associated with overall post-recurrence survival time. For this select group of patients, the surgical objective should be resection of all macroscopic disease.
Central East LHIN (Ontario)- Integration-Process slide/pdf file
Integration-Process_for_website.pdf (application/pdf Object)
There is no requirement of the LHIN or HSP provider to conduct a community engagement process
Sunday, January 04, 2009
Tragic results of suboptimal gynecologic cancer operations
Tragic results of suboptimal gynecologic cancer op...[Eur J Gynaecol Oncol. 2008] - PubMed Result
"CONCLUSION: If a gynecologist does not have enough experience or expertise about gynecological cancer operations, he or she must consider the possible harm that any surgical intervention might do, as the latin phrase 'primum non nocere' means and should refer patients to a gynecological oncology center without performing any surgery."
Prospective study of physical activity and the risk of ovarian cancer
Prospective study of physical activity and the ris...[Cancer Causes Control. 2008] - PubMed Result
"CONCLUSIONS: Neither moderate nor vigorous physical activity showed a statistically significant association with ovarian cancer in this large cohort of women."
Consideration of hereditary nonpolyposis colorectal cancer (HNPCC/Lynch Syndrome) in BRCA mutation negative familial ovarian cancers
Consideration of hereditary nonpolyposis colorecta...[Cancer. 2008] - PubMed Result
"CONCLUSIONS:: HNPCC should be considered when evaluating patients with suspected hereditary ovarian cancer who have had negative BRCA mutation testing"
Clinical trials in Canada: whose interests are paramount?
Clinical trials in Canada: whose interests are par...[Int J Health Serv. 2008] - PubMed Result
Clinical trials in Canada: whose interests are paramount?
More than 80 percent of clinical drug trials in Canada are funded by the pharmaceutical industry. This article evaluates the overall state of clinical trials in Canada and looks at the interplay between public and private interests. Health Canada has adopted standards developed by the International Conference on Harmonization, a body that is heavily influenced by industry. Commercial interests are increasingly involved in recruiting patients into clinical trials and in running these trials. It is in industry's interests to conduct drug tests on people for which it is easiest to see benefits. These interests are not fundamentally challenged by Health Canada's policy of issuing nonmandatory guidelines on who should and should not be included in clinical trials. The outcome of clinical trials is heavily influenced by commercial sponsorship, with the result that trials may favor corporate interests rather than the interests of the public. How Health Canada deals with that possibility is not known, because of its strict policy of treating clinical trial data as private property. If clinical trials are to serve the purpose for which they are designed, developing reliable and objective information about new drugs, then commercial interests cannot be allowed to take precedence over health interests.
Medical students' experiences with addicted patients: a web-based survey
Medical students' experiences with addicted patien...[Subst Abus. 2008] - PubMed Result
"Students reacted strongly to the psychosocial impact of addictions on patients, yet they viewed addiction as a personal choice, not an illness. Conclusion: Medical students are not being trained to diagnose addiction or provide advice and counseling. Medical schools need to provide students with positive clinical experiences supervised by physicians experienced in addictions."
Saturday, January 03, 2009
Can the preoperative Ca-125 level predict optimal cytoreduction in patients with advanced ovarian carcinoma? A single institution cohort study
Can the preoperative Ca-125 level predict optimal ...[Gynecol Oncol. 2009] - PubMed Result: "Can the preoperative Ca-125 level predict optimal cytoreduction in patients with advanced ovarian carcinoma? A single institution cohort study"
A contemporary analysis of ability of pre-op serum CA-125 to predict primary cytoreductive outcome in patients advanced ovarian, tubal & peritoneal
A contemporary analysis of the ability of preopera...[Gynecol Oncol. 2009] - PubMed Result
"A contemporary analysis of the ability of preoperative serum CA-125 to predict primary cytoreductive outcome in patients with advanced ovarian, tubal and peritoneal carcinoma"
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