2Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer) -- Vasen et al. 44 (6): 353 -- Journal of Medical Genetics

Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer) -- Vasen et al. 44 (6): 353 -- Journal of Medical Genetics

Table 2 Lifetime risk of cancer reported in families with an identified mismatch repair mutation

Colorectal cancer (men) 28–75%
Colorectal cancer (women) 24–52%
Endometrial cancer 27–71%
Ovarian cancer 3–13%
Gastric cancer 2–13%
Urinary tract cancer 1–12%
Brain tumour 1–4%
Bile duct/gallbladder cancer 2%
Small-bowel cancer 4–7%