Correspondence: Molecular Screening for Lynch Syndrome: From Bench to Bedside

Lynch syndrome is the most prevalent familial cancer. Screening
can prevent death from new colon and endometrial cancers among
the patients and family members. We urge the implementation of a
molecular screening for all colorectal cancer patients and suggest
taking advantage of BRAF and methylation analyses in MLH1-
negative cases to select the patients at highest risk.