abstract: Pharmacogenomics of taxane/platinum therapy in ovarian cancer

epigentics: The study of heritable changes in gene function that occur without a change in the DNA sequence

"CONCLUSIONS: Other mechanisms of variability, including epigenetic control of gene expression and copy number variation, may play important roles. In addition, nongenetic influences such as concurrent medications, and physiological and environmental factors could also affect individual responses to taxane and platinum therapy."