PLoS ONE: Risk of Ovarian Cancer and Inherited Variants in Relapse-Associated Genes Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Monday, February 01, 2010

PLoS ONE: Risk of Ovarian Cancer and Inherited Variants in Relapse-Associated Genes



"...We previously reported results of tumor mRNA expression studies which suggested that altered expression of a particular set of genes predicted response to chemotherapy among women with advanced-stage high-grade epithelial ovarian cancer.......Conclusions: "Tumor studies can reveal novel genes worthy of follow-up for cancer susceptibility. Here, we found that inherited markers in the gene encoding MSL1, part of a complex that modifies the histone H4, may decrease risk of invasive serous ovarian cancer."

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