CA 125 and the detection of recurrent ovarian cancer. Robert C. Bast Jr. 2010; Cancer - Wiley InterScience Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Monday, April 12, 2010

CA 125 and the detection of recurrent ovarian cancer. Robert C. Bast Jr. 2010; Cancer - Wiley InterScience



Commentary
CA 125 and the detection of recurrent ovarian cancer

A reasonably accurate biomarker for a difficult disease
Robert C. Bast Jr, MD
Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas


Abstract
Rising cancer antigen 125 (CA125) levels have been used to detect recurrence of ovarian cancer. A recent study questions the value of this practice, but the clinical trial has significant limitations and discounts the value of early detection to permit treatment of recurrence with novel and conventional agents.

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