News: AACR: Nodectomy Helps in Carcinosarcoma - in Meeting Coverage, AACR

"Lymphadenectomy was associated with significant improvement in survival (P<0.001) in patients with ovarian and uterine carcinosarcomas, but the procedure was not performed as often in those with ovarian disease.
"Improved survival observed in the lymphadenectomy group argues in favor of routinely performing lymph node dissection in patients with uterine and ovarian carcinosarcoma," Gunjal Garg, MD, of Detroit Medical Center, and colleagues concluded in a poster presentation at the American Association for Cancer Research.
Carcinosarcomas are malignant mixed mullerian tumors. Carcinosarcomas that arise in the female genital tract are rare but associated with poor prognosis. Previous studies demonstrated that tumors of similar histology and originating in nearby organs might be biologically distinct entities because of involvement with different molecular pathways, Garg and colleagues noted..."cont'd