Comparative effectiveness of screening and prevention strategies among BRCA1/2-affected mutation carriers Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

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Wednesday, July 21, 2010

Comparative effectiveness of screening and prevention strategies among BRCA1/2-affected mutation carriers



Conclusion: Our analysis suggested that among BRCA1/2 mutation carriers, prophylactic surgery would dominate or be cost effective compared to chemoprevention and screening. Annual screening with MRI and mammography was the most effective strategy because it was associated with the longest quality-adjusted survival, but it was also very expensive.

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