Detection of the HE4 protein in urine as a biomarker for ovariannext term neoplasms (abstract) Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us

Blog Archives: Nov 2004 - present

#ovariancancers



Special items: Ovarian Cancer and Us blog best viewed in Firefox

Search This Blog

Friday, August 20, 2010

Detection of the HE4 protein in urine as a biomarker for ovariannext term neoplasms (abstract)



Abstract The HE4 protein is overexpressed in ovarian carcinomas and can be detected in serum by an ELISA with sensitivity similar to CA125 and higher specificity for malignant disease. We now demonstrate that HE4 can also be detected in the urine at a specificity level of 94.4%, including 13/15 (86.6%) with stage I/II and 57/64 (89.0%) with stage III/IV disease and including 90.5% of patients with serous carcinoma. Assaying serum and urine from the same patients showed similar sensitivity. Our data indicate that measuring HE4 in urine may aid diagnosis and the monitoring of response to therapy.

2 comments :

  1. I’m inspired with the surpassing and preachy listing that you furnish in such little timing. what causes yellow urine

    ReplyDelete
  2. preachy ? ?
    definition: preach·y
    ˈprēCHē/
    having or revealing a tendency to give moral advice in a tedious or self-righteous way.

    ReplyDelete

Your comments?

Note: Only a member of this blog may post a comment.

2 comments :

  1. I’m inspired with the surpassing and preachy listing that you furnish in such little timing. what causes yellow urine

    ReplyDelete
  2. preachy ? ?
    definition: preach·y
    ˈprēCHē/
    having or revealing a tendency to give moral advice in a tedious or self-righteous way.

    ReplyDelete

Your comments?

Note: Only a member of this blog may post a comment.