Journal of Gynecologic Surgery: Splenectomy in Cytoreductive Surgery for Advanced Ovarian Cancer and Subsequent Intraperitoneal Chemotherapy

Objectives: The objective of this study was to determine the ability of patients with advanced ovarian cancer to tolerate intraperitoneal (IP) chemotherapy after having undergone optimal cytoreductive surgery (OCRS) requiring splenectomy.
Conclusions: Patients who undergo splenectomy at the time of OCRS are just as able as those who do not have a splenectomy to complete a full course of IP chemotherapy. The median PFS is comparable in the two groups.