Objective
To identify risk factors for the
presence of a non-invasive lesion of the fallopian tube in women with a
BRCA1 or BRCA2 mutation.
Conclusion
The
prevalence of tubal p53 signature and TIC (a tubal intra-epithelial carcinoma (TIC)) increases with age at
salpingectomy and with BMI. Oral contraceptive use is associated with a
decrease in the prevalence of TICs.
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